High-carbohydrate, high-fat diet–induced metabolic syndrome and cardiovascular remodeling in rats

SK Panchal, H Poudyal, A Iyer, R Nazer… - Journal of …, 2011 - journals.lww.com
The prevalence of metabolic syndrome including central obesity, insulin resistance,
impaired glucose tolerance, hypertension, and dyslipidemia is increasing. Development of …

The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes

M Wei, L Ong, MT Smith, FB Ross, K Schmid… - Heart, lung and …, 2003 - Elsevier
Background: Diabetes in humans induces chronic complications such as cardiovascular
damage, cataracts and retinopathy, nephropathy and polyneuropathy. The most common …

[HTML][HTML] Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate–, high fat–fed rats

H Poudyal, F Campbell, L Brown - The journal of nutrition, 2010 - Elsevier
Olive oil, an important component of the Mediterranean diet, produces cardioprotective
effects, probably due to both oleic acid and the polyphenols such as oleuropein and …

Lipid redistribution by α-linolenic acid-rich chia seed inhibits stearoyl-CoA desaturase-1 and induces cardiac and hepatic protection in diet-induced obese rats

H Poudyal, SK Panchal, J Waanders, L Ward… - The Journal of nutritional …, 2012 - Elsevier
Chia seeds contain the essential fatty acid, α-linolenic acid (ALA). This study has assessed
whether chia seeds attenuated the metabolic, cardiovascular and hepatic signs of a high …

Comparison of purple carrot juice and β-carotene in a high-carbohydrate, high-fat diet-fed rat model of the metabolic syndrome

H Poudyal, S Panchal, L Brown - British journal of nutrition, 2010 - cambridge.org
Anthocyanins, phenolic acids and carotenoids are the predominant phytochemicals present
in purple carrots. These phytochemicals could be useful in treatment of the metabolic …

Sustained release of engineered stromal cell–derived factor 1-α from injectable hydrogels effectively recruits endothelial progenitor cells and preserves ventricular …

JW MacArthur Jr, BP Purcell, Y Shudo, JE Cohen… - Circulation, 2013 - Am Heart Assoc
Background—Exogenously delivered chemokines have enabled neovasculogenic
myocardial repair in models of ischemic cardiomyopathy; however, these molecules have …

Atrial arrhythmia in ageing spontaneously hypertensive rats: unraveling the substrate in hypertension and ageing

DH Lau, NJ Shipp, DJ Kelly, S Thanigaimani, M Neo… - PloS one, 2013 - journals.plos.org
Background Both ageing and hypertension are known risk factors for atrial fibrillation (AF)
although the pathophysiological contribution or interaction of the individual factors remains …

Anti-inflammatory γ-and δ-tocotrienols improve cardiovascular, liver and metabolic function in diet-induced obese rats

WY Wong, LC Ward, CW Fong, WN Yap… - European journal of …, 2017 - Springer
Purpose This study tested the hypothesis that γ-and δ-tocotrienols are more effective than α-
tocotrienol and α-tocopherol in attenuating the signs of diet-induced metabolic syndrome in …

Right ventricular failure following chronic pressure overload is associated with reduction in left ventricular mass: evidence for atrophic remodeling

M Hardziyenka, ME Campian, HJ Reesink… - Journal of the American …, 2011 - jacc.org
Objectives: We sought to study whether patients with right ventricular failure (RVF)
secondary to chronic thromboembolic pulmonary hypertension (CTEPH) have reduced left …

Gender differences in adenine-induced chronic kidney disease and cardiovascular complications in rats

V Diwan, D Small, K Kauter… - American Journal of …, 2014 - journals.physiology.org
Gender contributes to differences in incidence and progression of chronic kidney disease
(CKD) and associated cardiovascular disease. To induce kidney damage in male and …