As an anti-inflammatory alkaloid, nicotine plays dual roles in treating diseases. Here we
reviewed the anti-inflammatory and pro-inflammatory effects of nicotine on inflammatory …

All nervous system pathologies (eg, neurodegenerative/demyelinating diseases and brain
tumours) develop neuroinflammation, a beneficial process during pathological events …

In several central nervous system diseases, it has been reported that inflammation may be
related to the etiologic process, therefore, therapeutic strategies are being implemented to …

Arecoline is a naturally occurring psychoactive alkaloid with partial agonism at nicotinic and
muscarinic acetylcholine receptors. Arecoline consumption is widespread, making it the …

Nicotinic acetylcholine receptors (nAChRs) are widely expressed in or on various cell types
and have diverse functions. In immune cells nAChRs regulate proliferation, differentiation …

Acetylcholine (ACh), as a classical neurotransmitter, regulates the neuronal network in
response to internal and external stimuli. In recent decades, the biology of ACh has been …

Pure nicotine impairs macrophage killing of Mycobacterium tuberculosis (MTB), but it is not
known whether the nicotine component in cigarette smoke (CS) plays a role. Moreover, the …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS). Although emerging evidence has shown that changes in …

Multiple sclerosis (MS) is an autoimmune and demyelinating disease of the central nervous
system. Although the etiology of MS is still unknown, both genetic and environmental factors …

Multiple Sclerosis (MS) is an autoimmune disease, having not fully understood aetiology,
and both genetic and environmental factors contribute to the pathogenesis of the disease …