While gap junctions support the exchange of a number of molecules between neighboring
cells, connexin hemichannels provide communication between the cytosol and the …

In mammalian tissues, at least two isozymes of 11β-hydroxysteroid dehydrogenase (11β-
HSD) catalyze the interconversion of hormonally active C11-hydroxylated corticosteroids …

Mineralocorticoid receptors, both when in tissue extracts and when recombinant-derived,
have equal affinity for the physiological mineralocorticoid aldosterone and for the …

Intercellular gap-junctional communication was measured using metabolic co-operation in
co-cultures of argininosuccinate synthetase-deficient and argininosuccinate lyase-deficient …

The history of licorice as an officinal plant dates back thousands of years, and licorice is still
appreciated as a medicinal root. Many of its endocrine properties can be derived from …

Pharmacological and physiological phenomena suggest that cells somewhere inside the
central nervous system are responsive to aldosterone. Here, we present the fundamental …

Triterpenoids isolated and characterized from various sources are reviewed. The newer
techniques used in their isolation and structure elucidation, the newer skeleton triterpenoids …

Liquorice abuse causes a syndrome of pseudohyperaldosteronism. Much less commonly,
glucocorticoid‐like effects have been reported. The electrolyte‐active principle of liquorice is …

1. 11β-Hydroxysteroid dehydrogenase is an enzyme complex consisting of 11β-
dehydrogenase and 11-oxoreductase responsible for the interconversion of cortisol to …

Abstract 18 beta-Glycyrrhetinic acid (GA) has been thought to be one of the major
metabolites that causes licorice-induced pseudoaldosteronism. However, we found no …