Oral nanomedicine: challenges and opportunities

B Deng, S Liu, Y Wang, B Ali, N Kong, T Xie… - Advanced …, 2024 - Wiley Online Library
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

Organoids: The current status and biomedical applications

S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

[HTML][HTML] Advanced human developmental toxicity and teratogenicity assessment using human organoid models

M Li, J Gong, L Gao, T Zou, J Kang, H Xu - … and Environmental Safety, 2022 - Elsevier
Tremendous progress has been made in the field of toxicology leading to the advance of
developmental toxicity assessment. Conventional animal models and in vitro two …

Penetration and translocation of functional inorganic nanomaterials into biological barriers

Y Cong, D Baimanov, Y Zhou, C Chen… - Advanced Drug Delivery …, 2022 - Elsevier
With excellent physicochemical properties, inorganic nanomaterials (INMs) have exhibited a
series of attractive applications in biomedical fields. Biological barriers prevent successful …

The DNA damage potential of quantum dots: Toxicity, mechanism and challenge

Y Yao, T Zhang, M Tang - Environmental Pollution, 2023 - Elsevier
Quantum dots (QDs) are semiconductor nanoparticles (1–10 nm) with excellent optical and
electrical properties. As QDs show great promise for applications in fields such as …

[HTML][HTML] Organoids and organoids-on-a-chip as the new testing strategies for environmental toxicology-applications & advantages

C Hu, S Yang, T Zhang, Y Ge, Z Chen, J Zhang… - Environment …, 2024 - Elsevier
An increasing number of harmful environmental factors are causing serious impacts on
human health, and there is an urgent need to accurately identify the toxic effects and …

Recent advances in the biological responses to nano-black phosphorus: understanding the importance of intrinsic properties and cell types

Q Zhao, IS Donskyi, Z Xiong, D Liu… - Environmental …, 2023 - ACS Publications
The production scalability and increasing demand for nano-black phosphorus materials
(nano-BPs) inevitably lead to their environmental leakage, thereby raising the risk of human …

Two-dimensional nanomaterials-added dynamism in 3D printing and bioprinting of biomedical platforms: Unique opportunities and challenges

B Gaihre, MA Potes, V Serdiuk, M Tilton, X Liu, L Lu - Biomaterials, 2022 - Elsevier
The nanomaterials research spectrum has seen the continuous emergence of two-
dimensional (2D) materials over the years. These highly anisotropic and ultrathin materials …

New insights into the safety assessment of quantum dots: potential release pathways, environmental transformations, and health risks

Q Liu, X Ding, Y Pang, Y Cao, J Lei, J Wu… - Environmental Science …, 2022 - pubs.rsc.org
Quantum dots (QDs), also known as “artificial atoms”, are a new class of engineering
nanoparticles. They are semiconductor nanocrystals composed of a few atoms and have …

Carbon nanotubes promote the development of intestinal organoids through regulating extracellular matrix viscoelasticity and intracellular energy metabolism

L Bao, X Cui, X Wang, J Wu, M Guo, N Yan, C Chen - ACS nano, 2021 - ACS Publications
The biological effect of engineered carbon nanotubes (CNTs) as beneficial biomaterials on
the intestine, especially on its development, remains unclear. Here, we investigated the …