NADPH oxidase family proteins: signaling dynamics to disease management
Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …
Roles of PRR-mediated signaling pathways in the regulation of oxidative stress and inflammatory diseases
P Li, M Chang - International journal of molecular sciences, 2021 - mdpi.com
Oxidative stress is a major contributor to the pathogenesis of various inflammatory diseases.
Accumulating evidence has shown that oxidative stress is characterized by the …
Accumulating evidence has shown that oxidative stress is characterized by the …
Muramyl dipeptide-based analogs as potential anticancer compounds: Strategies to improve selectivity, biocompatibility, and efficiency
E Iwicka, J Hajtuch, K Dzierzbicka… - Frontiers in …, 2022 - frontiersin.org
According to the WHO, cancer is the second leading cause of death in the world. This is an
important global problem and a major challenge for researchers who have been trying to …
important global problem and a major challenge for researchers who have been trying to …
Role and molecular mechanism of NOD2 in chronic non-communicable diseases
L Kong, Y Cao, Y He, Y Zhang - Journal of Molecular Medicine, 2024 - Springer
Nucleotide-binding oligomerization domain containing 2 (NOD2), located in the cell
cytoplasm, is a pattern recognition receptor belonging to the innate immune receptor family …
cytoplasm, is a pattern recognition receptor belonging to the innate immune receptor family …
Knockdown of circular RNA hsa_circ_0003204 inhibits oxidative stress and apoptosis through the miR-330-5p/Nod2 axis to ameliorate endothelial cell injury induced …
B Zhang, Y Zhang, R Li, Y Li, W Yan - Central European Journal of …, 2021 - termedia.pl
Results Hsa_circ_0003204 and Nod2 were upregulated while miR-330-5p was decreased
in ox-LDL-induced HAECs. Hsa_circ_0003204 depletion restrained the oxidative stress and …
in ox-LDL-induced HAECs. Hsa_circ_0003204 depletion restrained the oxidative stress and …
Giardia lamblia regulates the production of proinflammatory cytokines through activating the NOD2–Rip2–ROS signaling pathway in mouse macrophages
X Zhang, X Li, Y Yu, X Zhang, X Wang… - … and Cell Biology, 2022 - Wiley Online Library
Giardia lamblia is a zoonotic protozoan that causes the diarrheal illness giardiasis, with the
highest prevalence reported in the tropics and subtropics. Giardia is currently the most …
highest prevalence reported in the tropics and subtropics. Giardia is currently the most …
Peptides derived from rice α-globulin reduce atherosclerosis in apolipoprotein E-deficient mice by inhibiting TNF-α-induced vascular endothelial cells injury
LT Tong, Z Ju, L Wang, J Qiu, L Liu, X Zhou… - Journal of Functional …, 2019 - Elsevier
Rice α-globulin has been reported to possess anti-atherosclerotic activity, but the key
peptides in the rice α-globulin and the underlying mechanisms remain unknown. The anti …
peptides in the rice α-globulin and the underlying mechanisms remain unknown. The anti …
Cilostazol regulates the expressions of endothelin‑1 and endothelial nitric oxide synthase via activation of the p38 MAPK signaling pathway in HUVECs
Y Xue, X Li, Z Wang, Q Lv - Biomedical Reports, 2022 - spandidos-publications.com
Cilostazol is a selective inhibitor of phosphodiesterase type III that inhibits platelet
aggregation. The beneficial effects of cilostazol have been attributed not only to its …
aggregation. The beneficial effects of cilostazol have been attributed not only to its …
NOD2 induces VCAM-1 and ET-1 gene expression via NF-κB in human umbilical vein endothelial cells with muramyl dipeptide stimulation
K Ling-jun, Y Wang, Z Wang, L Qian-zhou - Herz, 2021 - search.proquest.com
Objectives Endothelial dysfunction is involved in various aspects of vascular biology and
different stages of cardiovascular diseases (CVDs). Nucleotide-binding oligomerization …
different stages of cardiovascular diseases (CVDs). Nucleotide-binding oligomerization …
NOD2 induziert VCAM-1-und ET-1-Genexpression über NF-κB in menschlichen Nabelvenenendothelzellen mit Muramyldipeptid-Stimulation
L Kong, Y Wang, Z Wang, Q Lv - Herz, 2021 - Springer
Objectives Endothelial dysfunction is involved in various aspects of vascular biology and
different stages of cardiovascular diseases (CVDs). Nucleotide-binding oligomerization …
different stages of cardiovascular diseases (CVDs). Nucleotide-binding oligomerization …