Nanoparticle-based delivery systems for vaccines
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …
vaccinations may have low immunogenicity and, in most situations, only provide partial …
Lipid nanoparticles: Different preparation techniques, characterization, hurdles, and strategies for the production of solid lipid nanoparticles and nanostructured lipid …
P Ganesan, D Narayanasamy - Sustainable Chemistry and Pharmacy, 2017 - Elsevier
The bioavailability of an orally administered drug primarily depends on its solubility in the
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …
Lipid-based nanoparticles for drug delivery systems
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have opened new
horizons in the pharmaceutical industry since they play a fundamental role in the field of …
horizons in the pharmaceutical industry since they play a fundamental role in the field of …
Comprehensive analysis of liposome formulation parameters and their influence on encapsulation, stability and drug release in glibenclamide liposomes
S Maritim, P Boulas, Y Lin - International journal of pharmaceutics, 2021 - Elsevier
An understanding of the factors that affect liposome size, drug loading, stability and drug
release is critical for the rational design of liposomes with desired pharmacokinetics and …
release is critical for the rational design of liposomes with desired pharmacokinetics and …
Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates
The rule of 5 (Ro5) is a set of in silico guidelines applied to drug discovery to prioritize
compounds with an increased likelihood of high oral absorption. It has been influential in …
compounds with an increased likelihood of high oral absorption. It has been influential in …
Biodegradable polymer nanogels for drug/nucleic acid delivery
Despite the extensive research on therapeutic delivery, many problems still exist on how to
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …
[HTML][HTML] Nanovaccines: a game changing approach in the fight against infectious diseases
The field of nanotechnology has revolutionised global attempts to prevent, treat, and
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …
Cell-based drug delivery systems and their in vivo fate
L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …
unique biological properties and self-powered functions, such as excellent biocompatibility …
Mechanisms of drug release from advanced drug formulations such as polymeric-based drug-delivery systems and lipid nanoparticles
GH Son, BJ Lee, CW Cho - Journal of Pharmaceutical Investigation, 2017 - Springer
Drug release from a polymeric nanocarrier is affected by several factors including the sort of
composition (drug, polymer, and excipient), the ratio of composition, physical or chemical …
composition (drug, polymer, and excipient), the ratio of composition, physical or chemical …
Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?
J Brouwers, ME Brewster, P Augustijns - Journal of pharmaceutical …, 2009 - Elsevier
Contemporary pharmaceutical pipelines are often highly populated with poorly water-
soluble drug candidates necessitating novel formulation technologies to provide dosage …
soluble drug candidates necessitating novel formulation technologies to provide dosage …