Cancer remains an elusive, highly complex disease and a global burden. Constant change
by acquired mutations and metabolic reprogramming contribute to the high inter-and …

ATP-binding cassette (ABC) transporters such as ABCB1, ABCG2, and ABCC1 are the
major players in drug efflux-mediated multidrug resistance (MDR), which severely affects the …

STING is an innate immune sensor for immune surveillance of viral/bacterial infection and
maintenance of an immune‐friendly microenvironment to prevent tumorigenesis. However, if …

Abstract Anlotinib (AL3818), a novel multi-targeted receptor tyrosine kinase inhibitor, has
recently been proven to be an antitumour drug. This study aimed to explore the antitumour …

Considerable evidence supports the role of oxidative stress in adult type 2 diabetes (T2D).
Due to increasing rates of pediatric obesity, lack of physical activity, and consumption of …

Introduction Biliary tract cancer (BTC), including intra-and extrahepatic cholangiocarcinoma
and gallbladder cancer, is a rare and highly difficult to manage human malignancy. Besides …

Gliomas are one of the most common primary malignant tumours of the central nervous
system (CNS), of which glioblastomas (GBMs) are the most common and destructive type …

Hyperuricemic nephropathy (HN) is renal injury caused by hyperuricemia (HUA). While
sleeve gastrectomy (SG) has shown promise in improving renal injury in patients with …

Objectives The association between single nucleotide polymorphisms (SNPs) of the
Catalase (CAT) gene and noise-induced hearing loss (NIHL) has been reported in several …

Simple Summary Anaplastic thyroid cancer (ATC) is the highest lethal type of thyroid cancer.
Regrettably, ATC patients respond poorly to multiple treatment strategies. Therefore, there is …