The heat-shock response is a mechanism of cellular protection against sudden adverse
environmental growth conditions and results in the prompt production of various heat-shock …

Members of the AAA+ protein superfamily contribute to many diverse aspects of protein
homeostasis in prokaryotic cells. As a fundamental component of numerous proteolytic …

Protein turnover is a tightly controlled process that is crucial for the removal of aberrant
polypeptides and for cellular signalling. Whereas ubiquitin marks eukaryotic proteins for …

Enterococcus is a diverse and rugged genus colonizing the gastrointestinal tract of humans
and numerous hosts across the animal kingdom. Enterococci are also a leading cause of …

In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …

Protein phosphorylation is a pivotal post-translational modification modulating various
cellular processes. In Gram-positive bacteria, the protein arginine kinase McsB, along with …

Protein modifications not only affect protein homeostasis but can also establish new cellular
protein functions and are important components of complex cellular signal sensing and …

Reversible protein phosphorylation is an important and ubiquitous protein modification in all
living cells. Here we report that protein phosphorylation on arginine residues plays a …

Fast adaptation to environmental changes ensures bacterial survival, and proteolysis
represents a key cellular process in adaptation. The Clp protease system is a multi …

DNA pumps play important roles in bacteria during cell division and during the transfer of
genetic material by conjugation and transformation. The FtsK/SpoIIIE proteins carry out the …