Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

Immunoinformatics-based potential multi-peptide vaccine designing against Jamestown Canyon Virus (JCV) capable of eliciting cellular and humoral immune …

M Shahab, S Aiman, A Alshammari, AF Alasmari… - International Journal of …, 2023 - Elsevier
Jamestown Canyon virus (JCV) is a deadly viral infection transmitted by various mosquito
species. This mosquito-borne virus belongs to Bunyaviridae family, posing a high public …

Revisiting the dimensions of universal vaccine with special focus on COVID-19: Efficacy versus methods of designing

P Jaishwal, K Jha, SP Singh - International Journal of Biological …, 2024 - Elsevier
Even though the use of SARS-CoV-2 vaccines during the COVID-19 pandemic showed
unprecedented success in a short time, it also exposed a flaw in the current vaccine design …

Immunoinformatics-driven in silico vaccine design for Nipah virus (NPV): Integrating machine learning and computational epitope prediction

M Shahab, MW Iqbal, A Ahmad, FM Alshabrmi… - Computers in Biology …, 2024 - Elsevier
The Nipah virus (NPV) is a highly lethal virus, known for its significant fatality rate. The virus
initially originated in Malaysia in 1998 and later led to outbreaks in nearby countries such as …

A cutting-edge immunoinformatics approach for design of multi-epitope oral vaccine against dreadful human malaria

M Pritam, G Singh, S Swaroop, AK Singh… - International Journal of …, 2020 - Elsevier
Human malaria is a pathogenic disease mainly caused by Plasmodium falciparum, which
was responsible for about 405,000 deaths globally in the year 2018. To date, several …

Immunoinformatics approach to design a novel subunit vaccine against visceral leishmaniasis

A Lari, N Lari, A Biabangard - International Journal of Peptide Research …, 2022 - Springer
Visceral leishmaniasis (VL) infection is mostly caused by Leishmania donovani and affects
countries worldwide. Despite the need for a safe and effective vaccine against leishmaniasis …

Prediction of an immunogenic peptide ensemble and multi-subunit vaccine for Visceral leishmaniasis using bioinformatics approaches

M Kupani, RK Pandey, S Vashisht, S Singh… - Heliyon, 2023 - cell.com
Visceral Leishmaniasis (VL) is a neglected tropical disease of public health importance in
the Indian subcontinent. Despite consistent elimination initiatives, the disease has not yet …

Computational design of candidate multi-epitope vaccine against SARS-CoV-2 targeting structural (S and N) and non-structural (NSP3 and NSP12) proteins

Z Ali, JV Cardoza, S Basak, U Narsaria… - Journal of …, 2023 - Taylor & Francis
The COVID-19 pandemic caused by SARS-CoV-2 virus has created a global damage and
has exposed the vulnerable side of scientific research towards novel diseases. The intensity …

A structural vaccinology approach for in silico designing of a potential self-assembled nanovaccine against Leishmania infantum

B Vakili, N Nezafat, M Negahdaripour… - Experimental …, 2022 - Elsevier
Visceral leishmaniasis (VL) remains a major public health problem across 98 countries. To
date, VL has no effective drug. Vaccines, as the most successful breakthroughs in medicine …

Design and characterization of high-affinity synthetic peptides as bioreceptors for diagnosis of cutaneous leishmaniasis

YA Prada, M Soler, F Guzmán, JJ Castillo… - Analytical and …, 2021 - Springer
Cutaneous leishmaniasis (CL) is one of the illnesses caused by Leishmania parasite
infection, which can be asymptomatic or severe according to the infecting Leishmania strain …