Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations
Background White matter hyperintensities (WMH), lacunes and microbleeds are regarded as
typical MRI expressions of cerebral small vessel disease (SVD) and they are highly …
typical MRI expressions of cerebral small vessel disease (SVD) and they are highly …
β-Amyloid, blood vessels, and brain function
EE Smith, SM Greenberg - Stroke, 2009 - Am Heart Assoc
Cerebrovascular disease and Alzheimer disease are common diseases of aging and
frequently coexist in the same brain. Accumulating evidence suggests that the presence of …
frequently coexist in the same brain. Accumulating evidence suggests that the presence of …
White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury
MS Fernando, JE Simpson, F Matthews, C Brayne… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—“Incidental” MRI white matter (WM) lesions, comprising
periventricular lesions (PVLs) and deep subcortical lesions (DSCLs), are common in the …
periventricular lesions (PVLs) and deep subcortical lesions (DSCLs), are common in the …
Imaging of amyloid burden and distribution in cerebral amyloid angiopathy
KA Johnson, M Gregas, JA Becker… - Annals of Neurology …, 2007 - Wiley Online Library
Objective Cerebrovascular deposition of β‐amyloid (cerebral amyloid angiopathy [CAA]) is a
major cause of hemorrhagic stroke and a likely contributor to vascular cognitive impairment …
major cause of hemorrhagic stroke and a likely contributor to vascular cognitive impairment …
Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhage
SM Greenberg, JA Eng, MM Ning, EE Smith, J Rosand - Stroke, 2004 - Am Heart Assoc
Background and Purpose—Small asymptomatic cerebral hemorrhages detectable by
gradient-echo MRI are common in patients with intracerebral hemorrhage (ICH), particularly …
gradient-echo MRI are common in patients with intracerebral hemorrhage (ICH), particularly …
Clinical manifestations of cerebral amyloid angiopathy–related inflammation
To explore the clinical effects of inflammation associated with vascular deposits of the
amyloid β peptide (Aβ), we analyzed 42 consecutive patients with pathologically diagnosed …
amyloid β peptide (Aβ), we analyzed 42 consecutive patients with pathologically diagnosed …
White matter lesion progression, brain atrophy, and cognitive decline: the Austrian stroke prevention study
R Schmidt, S Ropele, C Enzinger… - Annals of Neurology …, 2005 - Wiley Online Library
White matter lesions progress over time, but the clinical consequences are widely unknown.
Three‐hundred twenty‐nine elderly community‐dwelling volunteers underwent serial …
Three‐hundred twenty‐nine elderly community‐dwelling volunteers underwent serial …
Type 2 diabetes and cognitive impairment: linking mechanisms
JA Luchsinger - Journal of Alzheimer's Disease, 2012 - content.iospress.com
This manuscript provides a brief review of current concepts in the mechanisms potentially
linking type-2-diabetes (T2D) with cognitive impairment. Existing epidemiologic studies …
linking type-2-diabetes (T2D) with cognitive impairment. Existing epidemiologic studies …
Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy
GA Dierksen, ME Skehan, MA Khan, J Jeng… - Annals of …, 2010 - Wiley Online Library
Advanced cerebrovascular β‐amyloid deposition (cerebral amyloid angiopathy, CAA) is
associated with cerebral microbleeds, but the precise relationship between CAA burden and …
associated with cerebral microbleeds, but the precise relationship between CAA burden and …
Ischemic brain injury in cerebral amyloid angiopathy
YD Reijmer, SJ Van Veluw… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral amyloid angiopathy (CAA) is a common form of cerebral small vessel disease and
an important risk factor for intracerebral hemorrhage and cognitive impairment. While the …
an important risk factor for intracerebral hemorrhage and cognitive impairment. While the …