Spatial multi-omic studies have emerged as a promising approach to comprehensively
analyze cells in tissues, enabling the joint analysis of multiple data modalities like …

We present a spatial omics approach that combines histology, mass spectrometry imaging
and spatial transcriptomics to facilitate precise measurements of mRNA transcripts and low …

Gene expression profiling of tissue cells with spatial context is in high demand to reveal cell
types, locations, and intercellular or molecular interactions for physiological and …

Recent advances in spatial omics have expanded the spectrum of profiled molecular
categories beyond transcriptomics. However, many of these technologies are constrained by …

BACKGROUND Mammalian reproduction requires the fusion of two specialized cells: an
oocyte and a sperm. In addition to producing gametes, the reproductive system also …

DNA adducts and strand breaks are induced by various exogenous and endogenous
agents. Accumulation of DNA damage is implicated in many disease processes, including …

The potential of probiotics to benefit digestion has been widely reported, while its utilization
in high-risk patients and potential adverse reactions have focused interest on postbiotics. A …

Spatial transcriptomics (ST) enables interrogating the molecular composition of tissue with
ever-increasing resolution, depth, and sensitivity. However, costs, rapidly evolving …

Tissues are dynamic and complex biological systems composed of specialized cell types
that interact with each other for proper biological function. To comprehensively characterize …

Neurodegenerative disorders are typically characterized by late onset progressive damage
to specific (sub) populations of cells of the nervous system that are essential for mobility …