The establishment of the coronary circulation is critical for the development of the embryonic
heart. Over the last several years, there has been tremendous progress in elucidating the …

Epithelial-to-mesenchymal transition (EMT) is a key biological process involved in a
multitude of developmental and pathological events. It is characterized by the progressive …

Secreted factors from the epicardium are believed to be important in directing heart
ventricular cardiomyocyte proliferation and morphogenesis, although the specific factors …

Trophic factors secreted both from the endocardium and epicardium regulate appropriate
growth of the myocardium during cardiac development. Epicardially-derived cells play also a …

Over time, peritoneal dialysis results in functional and structural alterations of the peritoneal
membrane, but the underlying mechanisms and whether these changes are reversible are …

Aberrant activation of Ras/Raf/mitogen-activated protein kinase (MAPK) signaling is
frequently linked to metastatic prostate cancer (PCa); therefore, the characterization of …

During cardiac development, a subpopulation of epicardial cells migrates into the heart as
part of the epicardial epithelial-mesenchymal transition (EMT) and differentiates into smooth …

In our study, we found that bone morphogenetic protein 4 (BMP4) has a novel effect as an
inducer of epithelial‐mesenchymal transition (EMT) on Panc‐1 cells, a human pancreatic …

Background In the airways, mast cells are present in close vicinity to epithelial cells, and
they can interact with each other via multiple factors, including extracellular vesicles (EVs) …

Adult epicardial cells are required for endogenous cardiac repair. After myocardial injury,
they are reactivated, undergo epithelial-to-mesenchymal transformation (EMT) and migrate …