Referee: R. Rej, New York State Dept. of Health, Albany, NY Serum gamma-glutamyl
transferase (GGT) has been widely used as an index of liver dysfunction and marker of …

Oxidative stress is an unavoidable consequence of life in an oxygen‐rich atmosphere.
Oxygen radicals and other activated oxygen species are generated as by‐products of …

Inflammatory lung diseases are characterized by chronic inflammation and
oxidant/antioxidant imbalance, a major cause of cell damage. The development of an …

The primary role of cellular gamma glutamyltransferase (GGT) is to metabolize extracellular
reduced glutathione (GSH), allowing for precursor amino acids to be assimilated and …

Having long been regarded as just a member in the cellular antioxidant systems, as well as
a clinical biomarker of hepatobiliary diseases and alcohol abuse, gamma …

The mechanisms of thiol metabolism and chemistry have particular relevance to both
cellular defenses against toxicant exposure and to redox signaling. Here, we will focus on …

Abstract Background: γ-Glutamyltransferase (GGT), which maintains cellular concentrations
of glutathione, may be a marker of oxidative stress, and GGT itself may produce oxidative …

Redox biology has evolved from studies of the pathology that involves oxidants to an
understanding of how oxidants participate in normal as well as aberrant signal transduction …

Glutathione (GSH), a ubiquitous tripeptide thiol, is a vital intra-and extracellular protective
antioxidant in the lungs. The rate-limiting enzyme in GSH synthesis is γ-glutamylcysteine …

Abstract Aims/Hypothesis Gamma-glutamyltransferase (GGT) is located on the external
surface of most cells and mediates the uptake of gluthathione, an important component of …