Bridged nucleic acids reloaded
A Soler-Bistué, A Zorreguieta, ME Tolmasky - Molecules, 2019 - mdpi.com
Oligonucleotides are key compounds widely used for research, diagnostics, and
therapeutics. The rapid increase in oligonucleotide-based applications, together with the …
therapeutics. The rapid increase in oligonucleotide-based applications, together with the …
Cytokine rs361525, rs1800750, rs1800629, rs1800896, rs1800872, rs1800795, rs1800470, and rs2430561 SNPs in relation with prognostic factors in acute myeloid …
Background Cytokines were correlated with survival and disease progression in acute
myeloid leukemia (AML). We aimed to evaluate the multivariate effect of TNF‐α rs361525 …
myeloid leukemia (AML). We aimed to evaluate the multivariate effect of TNF‐α rs361525 …
Acute myeloid leukemia with DNMT3A mutations
Y Li, B Zhu - Leukemia & Lymphoma, 2014 - Taylor & Francis
Acute myeloid leukemia (AML), a type of blood cancer, is characterized by an increase in the
number of abnormal white blood cells in the bone marrow, frequently causing hematopoietic …
number of abnormal white blood cells in the bone marrow, frequently causing hematopoietic …
From six gene polymorphisms of the antioxidant system, only GPX Pro198Leu and GSTP1 Ile105Val modulate the risk of acute myeloid leukemia
Oxidative stress might contribute to the occurrence of cancers, including the hematological
ones. Various genetic polymorphisms were shown to increase the quantity of reactive …
ones. Various genetic polymorphisms were shown to increase the quantity of reactive …
Influence of XPC, XPD, XPF, and XPG gene polymorphisms on the risk and the outcome of acute myeloid leukemia in a Romanian population
Abstract XPC, XPD, XPF, and XPG genes are implicated in the nucleotide excision repair
(NER) system. Gene polymorphisms in NER repair system may influence the individual's …
(NER) system. Gene polymorphisms in NER repair system may influence the individual's …
[PDF][PDF] Simultaneous FLT3, NPM1 and DNMT3A mutations in adult patients with acute myeloid leukemia–case study
Background: Nowadays, cytogenetics and molecular genetics, but not only, are mandatory
in acute myeloid leukemia (AML) management, as a consequence of their impact on AML …
in acute myeloid leukemia (AML) management, as a consequence of their impact on AML …
Do mutations in DNMT3A/3B affect global DNA hypomethylation among benzene‐exposed workers in Southeast China?: effects of mutations in DNMT3A/3B on global …
G Zhang, Y Lu, B Ji, J Ren, P Sun… - Environmental and …, 2017 - Wiley Online Library
Global DNA hypomethylation is commonly observed in benzene‐exposed workers, but the
underlying mechanisms remain unclear. We sought to discover the relationships among …
underlying mechanisms remain unclear. We sought to discover the relationships among …
Rapid Detection of DNMT3A R882 Mutations in Hematologic Malignancies Using a Novel Bead-Based Suspension Assay with BNA(NC) Probes
V Shivarov, M Ivanova, E Naumova - PLoS One, 2014 - journals.plos.org
Mutations in the human DNA methyl transferase 3A (DNMT3A) gene are recurrently
identified in several hematologic malignancies such as Philadelphia chromosome-negative …
identified in several hematologic malignancies such as Philadelphia chromosome-negative …
[PDF][PDF] Presence of copy number aberration and clinical prognostic factors in patients with acute myeloid leukemia: An analysis of effect modification
ABSTRACT INTRODUCTION Acute myeloid leukemia (AML) is characterized by multiple
acquired genetic events, chromosomal abnormalities such as copy number aberrations …
acquired genetic events, chromosomal abnormalities such as copy number aberrations …
[HTML][HTML] TERT rs2853669 as a predictor for overall survival in patients with acute myeloid leukaemia
Results TERT rs2736100 and rs2853669 were not associated with AML risk in the
codominant, dominant, recessive, or allelic models. Multivariate Cox regression showed that …
codominant, dominant, recessive, or allelic models. Multivariate Cox regression showed that …