[HTML][HTML] An overview on the potential of natural products as ureases inhibitors: A review

LV Modolo, AX de Souza, LP Horta, DP Araujo… - Journal of Advanced …, 2015 - Elsevier
Ureases, enzymes that catalyze urea hydrolysis, have received considerable attention for
their impact on living organisms' health and life quality. On the one hand, the persistence of …

Flavonoids and related privileged scaffolds as potential urease inhibitors: a review

MM Al-Rooqi, EU Mughal, QA Raja, EM Hussein… - RSC …, 2023 - pubs.rsc.org
Infections caused by bacteria are a significant issue on a global scale, and imperative action
is required to discover novel or improved therapeutic agents. Flavonoids are a class of plant …

[PDF][PDF] Psidium guajava (Guava): A plant of multipurpose medicinal applications

SM Barbalho, FMV Farinazzi-Machado… - Med Aromat …, 2012 - researchgate.net
1Department of Biochemistry and Pharmacology, School of Medicine, University of Marília
(UNIMAR), Av. Higino Muzzi Filho 1001, Marília 15525-902, SP, Brazil. 2Department of …

An overview on the synthetic urease inhibitors with structure-activity relationship and molecular docking

W Yang, Q Feng, Z Peng, G Wang - European Journal of Medicinal …, 2022 - Elsevier
Urease is a kind of enzyme which could be found in various bacteria, fungi, plants, and
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …

Phenolic contents and in vitro investigation of the antioxidant, enzyme inhibitory, photoprotective, and antimicrobial effects of the organic extracts of Pelargonium …

S El Aanachi, L Gali, SN Nacer, C Bensouici… - Biocatalysis and …, 2020 - Elsevier
Pelargonium graveolens is an aromatic plant highly appreciated for its essential oil and
used to treat various illnesses. The present work focuses on the study of certain …

[PDF][PDF] Effectiveness of the use of urease inhibitors in agriculture: a review

D Matczuk, A Siczek - International Agrophysics, 2021 - bibliotekanauki.pl
Urea is one of the most popular fertilizers in the world. In 2018, the global production
capacity of urea reached the level of 210 million metric tonnes. Due to the fact that the world …

Novel thiobarbiturates as potent urease inhibitors with potential antibacterial activity: Design, synthesis, radiolabeling and biodistribution study

HG Abdulwahab, MF Harras, NG El Menofy… - Bioorganic & Medicinal …, 2020 - Elsevier
Urease enzyme is a virulence factor that helps in colonization and maintenance of highly
pathogenic bacteria in human. Hence, the inhibition of urease enzymes is well-established …

Structurally diversified heterocycles and related privileged scaffolds as potential urease inhibitors: a brief overview

A Ibrar, I Khan, N Abbas - Archiv der Pharmazie, 2013 - Wiley Online Library
Ureases have emerged as significant virulence factors implicated in the pathogenesis of
many clinical conditions such as pyelonephritis, hepatic coma, peptic ulceration, and the …

Synthesis, structure–activity relationship analysis and kinetics study of reductive derivatives of flavonoids as Helicobacter pylori urease inhibitors

ZP Xiao, ZY Peng, JJ Dong, J He, H Ouyang… - European journal of …, 2013 - Elsevier
In a continuing study for discovering urease inhibitors based on flavonoids, nineteen
reductive derivatives of flavonoids were synthesized and evaluated against Helicobacter …

In vitro study of the antioxidant, photoprotective, anti-tyrosinase, and anti-urease effects of methanolic extracts from leaves of six Moroccan Lamiaceae

S El Aanachi, L Gali, S Rammali, C Bensouici… - Journal of Food …, 2021 - Springer
Abstract Six Lamiaceae from Morocco were screened for their antioxidant, photoprotective,
anti-tyrosinase, and anti-urease effects in the aim to assess their possible use as a source of …