Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted
disease caused by tobacco smoking in genetically susceptible individuals has been …
disease caused by tobacco smoking in genetically susceptible individuals has been …
Impact of parental exposure on offspring health in humans
The possibility that parental life experiences and environmental exposures influence mental
and physical health across generations is an important concept in biology and medicine …
and physical health across generations is an important concept in biology and medicine …
[HTML][HTML] Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood
IN Kuiper, C Svanes, I Markevych, S Accordini… - Environment …, 2021 - Elsevier
Objectives To investigate if air pollution and greenness exposure from birth till adulthood
affects adult asthma, rhinitis and lung function. Methods: We analysed data from 3428 …
affects adult asthma, rhinitis and lung function. Methods: We analysed data from 3428 …
Trends in smoking initiation in Europe over 40 years: a retrospective cohort study
Background Tobacco consumption is the largest avoidable health risk. Understanding
changes of smoking over time and across populations is crucial to implementing health …
changes of smoking over time and across populations is crucial to implementing health …
Cigarette smoking significantly alters sperm DNA methylation patterns
TG Jenkins, ER James, DF Alonso, JR Hoidal… - …, 2017 - Wiley Online Library
Numerous health consequences of tobacco smoke exposure have been characterized, and
the effects of smoking on traditional measures of male fertility are well described. However, a …
the effects of smoking on traditional measures of male fertility are well described. However, a …
Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders
S Yeshurun, AJ Hannan - Molecular Psychiatry, 2019 - nature.com
In recent years, striking new evidence has demonstrated non-genetic inheritance of
acquired traits associated with parental environmental exposures. In particular, this …
acquired traits associated with parental environmental exposures. In particular, this …
A three-generation study on the association of tobacco smoking with asthma
S Accordini, L Calciano, A Johannessen… - International journal …, 2018 - academic.oup.com
Background Mothers' smoking during pregnancy increases asthma risk in their offspring.
There is some evidence that grandmothers' smoking may have a similar effect, and …
There is some evidence that grandmothers' smoking may have a similar effect, and …
Fathers' preconception smoking and offspring DNA methylation
NT Kitaba, GTM Knudsen, A Johannessen… - Clinical …, 2023 - Springer
Background Experimental studies suggest that exposures may impact respiratory health
across generations via epigenetic changes transmitted specifically through male germ cells …
across generations via epigenetic changes transmitted specifically through male germ cells …
Paternal preconception modifiable risk factors for adverse pregnancy and offspring outcomes: a review of contemporary evidence from observational studies
Background The preconception period represents transgenerational opportunities to
optimize modifiable risk factors associated with both short and long-term adverse health …
optimize modifiable risk factors associated with both short and long-term adverse health …
Measurement error is often neglected in medical literature: a systematic review
Objectives In medical research, covariates (eg, exposure and confounder variables) are
often measured with error. While it is well accepted that this introduces bias and imprecision …
often measured with error. While it is well accepted that this introduces bias and imprecision …