The emerging field of pancreatic tissue engineering: A systematic review and evidence map of scaffold materials and scaffolding techniques for insulin-secreting cells
GA Salg, NA Giese, M Schenk… - Journal of tissue …, 2019 - journals.sagepub.com
A bioartificial endocrine pancreas is proposed as a future alternative to current treatment
options. Patients with insulin-secretion deficiency might benefit. This is the first systematic …
options. Patients with insulin-secretion deficiency might benefit. This is the first systematic …
The preclinical and clinical progress of cell sheet engineering in regenerative medicine
D Hu, X Li, J Li, P Tong, Z Li, G Lin, Y Sun… - Stem Cell Research & …, 2023 - Springer
Cell therapy is an accessible method for curing damaged organs or tissues. Yet, this
approach is limited by the delivery efficiency of cell suspension injection. Over recent years …
approach is limited by the delivery efficiency of cell suspension injection. Over recent years …
Therapeutic strategies for modulating the extracellular matrix to improve pancreatic islet function and survival after transplantation
Abstract Purposes of Review Extracellular matrix (ECM) components modulate the
interaction between pancreatic islet cells. During the islet isolation prior to transplantation as …
interaction between pancreatic islet cells. During the islet isolation prior to transplantation as …
Recent advances in the design of implantable insulin secreting heterocellular islet organoids
Islet transplantation has proved one of the most remarkable transmissions from an
experimental curiosity into a routine clinical application for the treatment of type I diabetes …
experimental curiosity into a routine clinical application for the treatment of type I diabetes …
Engineering β cell replacement therapies for type 1 diabetes: biomaterial advances and considerations for macroscale constructs
MJ Quizon, AJ García - Annual Review of Pathology …, 2022 - annualreviews.org
While significant progress has been made in treatments for type 1 diabetes (T1D) based on
exogenous insulin, transplantation of insulin-producing cells (islets or stem cell–derived β …
exogenous insulin, transplantation of insulin-producing cells (islets or stem cell–derived β …
Magnetically Actuated SiCN‐Based Ceramic Microrobot for Guided Cell Delivery
A silicon carbonitride (SICN) ceramic microrobot, biocompatible and magnetically activable,
is developed for the delivery of viable cells to defective tissue by sequential steps of …
is developed for the delivery of viable cells to defective tissue by sequential steps of …
Fibroblasts accelerate islet revascularization and improve long-term graft survival in a mouse model of subcutaneous islet transplantation
M Perez-Basterrechea, MM Esteban, M Alvarez-Viejo… - PLoS …, 2017 - journals.plos.org
Pancreatic islet transplantation has been considered for many years a promising therapy for
beta-cell replacement in patients with type-1 diabetes despite that long-term clinical results …
beta-cell replacement in patients with type-1 diabetes despite that long-term clinical results …
An engineered cell sheet composed of human islets and human fibroblast, bone marrow–derived mesenchymal stem cells, or adipose–derived mesenchymal stem …
Background: We previously reported the utility of engineered cell sheets composed of
human islets and supporting cells in vitro and in vivo. It is unclear which type of supporting …
human islets and supporting cells in vitro and in vivo. It is unclear which type of supporting …
Use of additives, scaffolds and extracellular matrix components for improvement of human pancreatic islet outcomes in vitro: A systematic review
NE Lemos, LA Brondani, C Dieter, J Rheinheimer… - Islets, 2017 - Taylor & Francis
Pancreatic islet transplantation is an established treatment to restore insulin independence
in type 1 diabetic patients. Its success rates have increased lately based on improvements in …
in type 1 diabetic patients. Its success rates have increased lately based on improvements in …