Pathogenesis of respiratory viral and fungal coinfections
Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …
[HTML][HTML] Fibrin (ogen) in human disease: both friend and foe
Fibrinogen is an abundant protein synthesized in the liver, present in human blood plasma
at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 …
at concentrations ranging from 1.5-4 g/L in healthy individuals with a normal half-life of 3-5 …
Protease allergens as initiators–regulators of allergic inflammation
Tremendous progress in the last few years has been made to explain how seemingly
harmless environmental proteins from different origins can induce potent Th2‐biased …
harmless environmental proteins from different origins can induce potent Th2‐biased …
[HTML][HTML] Candida albicans elicits protective allergic responses via platelet mediated T helper 2 and T helper 17 cell polarization
Y Wu, Z Zeng, Y Guo, L Song, JE Weatherhead… - Immunity, 2021 - cell.com
Fungal airway infection (airway mycosis) is an important cause of allergic airway diseases
such as asthma, but the mechanisms by which fungi trigger asthmatic reactions are poorly …
such as asthma, but the mechanisms by which fungi trigger asthmatic reactions are poorly …
Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer
Chronic exposure to airborne carbon black ultrafine (nCB) particles generated from
incomplete combustion of organic matter drives IL-17A–dependent emphysema. However …
incomplete combustion of organic matter drives IL-17A–dependent emphysema. However …
Contribution of adaptive immunity to human COPD and experimental models of emphysema
F Kheradmand, Y Zhang, DB Corry - Physiological Reviews, 2023 - journals.physiology.org
The pathophysiology of chronic obstructive pulmonary disease (COPD) and the undisputed
role of innate immune cells in this condition have dominated the field in the basic research …
role of innate immune cells in this condition have dominated the field in the basic research …
[HTML][HTML] Fungal-mediated lung allergic airway disease: The critical role of macrophages and dendritic cells
J Furlong-Silva, PC Cook - PLoS pathogens, 2022 - journals.plos.org
Fungi are abundant in the environment, causing our lungs to be constantly exposed to a
diverse range of species. While the majority of these are cleared effectively in healthy …
diverse range of species. While the majority of these are cleared effectively in healthy …
[HTML][HTML] Material matters: exploring the interplay between natural biomaterials and host immune system
AS Tripathi, MEA Zaki, SA Al-Hussain… - Frontiers in …, 2023 - frontiersin.org
Biomaterials are widely used for various medical purposes, for instance, implants, tissue
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …
[HTML][HTML] Novel mechanistic insights underlying fungal allergic inflammation
Y Zheng, EV Dang - PLoS Pathogens, 2023 - journals.plos.org
The worldwide prevalence of asthma and allergic disorders (allergic rhinitis, atopic
dermatitis, food allergy) has been steadily rising in recent decades. It is now estimated that …
dermatitis, food allergy) has been steadily rising in recent decades. It is now estimated that …
[HTML][HTML] Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis
The fungal pathogen Candida albicans is linked to chronic brain diseases such as
Alzheimer's disease (AD), but the molecular basis of brain anti-Candida immunity remains …
Alzheimer's disease (AD), but the molecular basis of brain anti-Candida immunity remains …