Cancer is considered a life-threatening disease, and several factors are involved in its
development. Chemokines are small proteins that physiologically exert pivotal roles in …

Head and neck squamous cell carcinoma (HNSCC) is the 9 th most common malignant
tumor in the world. Based on the etiology, HNSCC has two main subtypes: human …

Due to its molecular heterogeneity and infiltrative nature, glioblastoma multiforme (GBM) is
notoriously resistant to traditional and experimental therapeutics. To overcome these …

Background Tumor-induced lymphangiogenesis facilitates breast cancer progression by
generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph …

Subtilase cytotoxin (SubAB) that selectively cleaves BiP/GRP78 triggers the unfolded protein
response (UPR) and protects mice from endotoxic lethality and collagen arthritis. We found …

Purpose This study aimed to investigate the biological roles of fibronectin 1 (FN1) in head
and neck squamous cell carcinoma (HNSCC) and its effects on macrophage M2 …

CC chemokine receptor 7 (CCR7) was one of the first two chemokine receptors that were
found to be upregulated in breast cancers. Chemokine receptors promote chemotaxis of …

Purpose miRNAs can play vital role in migration, invasion and proliferation in Squamous cell
carcinoma of head and neck (SCCHN). In our study, we attempted to validate the expression …

Migration and invasion of tumor cells are essential prerequisites for the formation of
metastasis in malignant diseases. Previously, we have reported that CC chemokine receptor …

Previously, we confirmed that CC chemokine receptor 7 (CCR7) promotes cell proliferation
via the extracellular signal-regulated kinase (ERK) pathway, but its role in apoptosis of non …