▪ Abstract Phenotypic variation for quantitative traits results from the segregation of alleles at
multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and …

Publisher Summary This chapter discusses the ecdysone receptors and their biological
actions. It also summarizes the insect endocrinology and the roles of these steroids in the …

Abstract The Berkeley Drosophila Genome Project (BDGP) strives to disrupt each
Drosophila gene by the insertion of a single transposable element. As part of this effort …

The generation of membrane domains with distinct protein constituents is a hallmark of cell
polarization. In epithelia, segregation of membrane proteins into apical and basolateral …

The senseless (sens) gene is required for proper development of most cell types of the
embryonic and adult peripheral nervous system (PNS) of Drosophila. Sens is a nuclear …

Here we report the description of the Drosophila gene futsch, which encodes a protein
recognized by the monoclonal antibody 22C10 that has been widely used to visualize …

Angelman syndrome (AS) is a severe genetic disorder caused by mutations or deletions of
the maternally inherited UBE3A gene. UBE3A encodes an E3 ubiquitin ligase that is …

Gfi1 was first identified as causing interleukin 2-independent growth in T cells and
lymphomagenesis in mice. Much work has shown that Gfi1 and Gfi1b, a second mouse …

The Extradenticle (Exd) protein in Drosophila acts as a cofactor to homeotic proteins. Its
nuclear localization is regulated. We report the cloning of the Drosophila homothorax (hth) …

Cytokinesis ensures the successful completion of the cell cycle and distribution of
chromosomes, organelles, and cytoplasm between daughter cells. It is accomplished by …