Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …

Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

Aims/hypothesis Antenatal obesity and associated gestational diabetes (GDM) are
increasing worldwide. While pre-existing insulin resistance is implicated in GDM in obese …

Metabolic profiles of amniotic fluid and maternal blood are sources of valuable information
about fetus development and can be potentially useful in diagnosis of pregnancy disorders …

Obese women, on average, give birth to babies with high fat mass. Placental lipid
metabolism alters fetal lipid delivery, potentially moderating neonatal adiposity, yet how it is …

A standardized data workflow is described for large-scale serum metabolomic studies using
multisegment injection-capillary electrophoresis-mass spectrometry. Multiplexed …

Background The in-utero environment affects fetal development; it is vital to understand how
maternal diet during pregnancy influences childhood body composition. While research …

Major alterations in metabolism occur during pregnancy enabling the mother to provide
adequate nutrients to support infant development, affecting birth weight (BW) and potentially …

Background Lipids play a vital role in health and disease, but changes to their circulating
levels and the link with obesity remain poorly characterized in expecting mothers and their …

Fatty acid metabolism and oxidation capacity in the placenta, which likely affects the rate
and composition of lipid delivered to the fetus remains poorly understood. Long chain …