Expression profile of miRs in mesial temporal lobe epilepsy: systematic review

KD Yakovleva, DV Dmitrenko, IS Panina… - International Journal of …, 2022 - mdpi.com
Temporal lobe epilepsy (TLE) is one of the most common forms of focal epilepsy in children
and adults. TLE is characterized by variable onset and seizures. Moreover, this form of …

The emerging role of miRNAs in epilepsy: From molecular signatures to diagnostic potential

SSA Mageed, AA Rashad, SS Elshaer… - … -Research and Practice, 2024 - Elsevier
Epilepsy is a medical condition characterized by intermittent seizures accompanied by
changes in consciousness. Epilepsy significantly impairs the daily functioning and overall …

The role of Rho/ROCK in epileptic seizure-related neuronal damage

Z Wang, D Ren, P Zheng - Metabolic Brain Disease, 2022 - Springer
Epilepsy is one of the most severe neurological disorders characterized by spontaneous
recurrent seizures. Although more than two-thirds of patients can be cured with anti-epileptic …

miRNAs in epilepsy: A review from molecular signatures to therapeutic intervention

M Jeelani - International Journal of Biological Macromolecules, 2024 - Elsevier
Epilepsy is a medical disorder marked by sporadic seizures accompanied by alterations in
consciousness. The molecular mechanisms responsible for epilepsy and the factors …

Differential expression of miR-34a, 451, 1260, 1275 and 1298 in the neocortex of patients with mesial temporal lobe epilepsy

D Organista-Juárez, A Jiménez, L Rocha… - Epilepsy Research, 2019 - Elsevier
Mesial temporal lobe epilepsy (mTLE) is the most common epilepsy syndrome which will
eventually become pharmacologically intractable partial-onset seizures. Regulation of gene …

Pentylenetetrazole-induced kindling rat model: miR-182 and miR-27b-3p mediated neuroprotective effect of thymoquinone in the hippocampus

M Pala, I Meral, N Pala Acikgoz… - Neurological …, 2022 - Taylor & Francis
Objectives: Epilepsy is a neurological disease that pathologically affects brain functions. The
epileptic hippocampus has modified microRNA (miRNA) levels. Therefore, we aimed to …

Downregulatory effect of miR-342-3p on epileptogenesis in the PTZ-kindling model

M Pala, I Meral, N Pala Acikgoz… - Molecular Biology …, 2022 - Springer
Background Epileptogenesis is a process that results in neurons firing abnormally, causing
seizures. Increasing evidence has shown that miRNAs expressed in the epileptic …

Upregulation of microRNA-96 alleviates the neurological damage in acute seizure rats by down-regulating RAC1 and inhibiting the activation of RhoA/ROCK …

Z Wang, W Jiang, D Ren, W Chen, P Zheng - 2019 - researchsquare.com
Objective Today, the research about the involvement of non-coding RNAs on neurological
disorders is still scarce. Hence, we aimed to investigate the effect of miR-96 targeted RAC1 …