A systematic review of the evidence for deprescribing interventions among older people living with frailty
Background Older people living with frailty are often exposed to polypharmacy and potential
harm from medications. Targeted deprescribing in this population represents an important …
harm from medications. Targeted deprescribing in this population represents an important …
Interventions to improve the appropriate use of polypharmacy for older people
A Rankin, CA Cadogan, SM Patterson… - Cochrane Database …, 2018 - cochranelibrary.com
Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …
associated with negative health outcomes. Choosing the best interventions to improve …
Medication review interventions to reduce hospital readmissions in older people
L Dautzenberg, L Bretagne, HL Koek… - Journal of the …, 2021 - Wiley Online Library
Objective To assess the efficacy of medication review as an isolated intervention and with
several co‐interventions for preventing hospital readmissions in older adults. Methods Ovid …
several co‐interventions for preventing hospital readmissions in older adults. Methods Ovid …
Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: a randomised controlled trial …
S Verdoorn, HF Kwint, JW Blom, J Gussekloo… - Plos …, 2019 - journals.plos.org
Background Clinical medication reviews (CMRs) are increasingly performed in older
persons with multimorbidity and polypharmacy to reduce drug-related problems (DRPs) …
persons with multimorbidity and polypharmacy to reduce drug-related problems (DRPs) …
International core outcome set for clinical trials of medication review in multi-morbid older patients with polypharmacy
Background Comparisons of clinical trial findings in systematic reviews can be hindered by
the heterogeneity of the outcomes reported. Moreover, the outcomes that matter most to …
the heterogeneity of the outcomes reported. Moreover, the outcomes that matter most to …
A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of …
Background Inappropriate use of multiple medicines (inappropriate polypharmacy) is a
major challenge in older people with consequences of increased prevalence and severity of …
major challenge in older people with consequences of increased prevalence and severity of …
Process, impact and outcomes of medication review in Australian residential aged care facilities: A systematic review
Objective To systematically review literature reporting processes, impact and outcomes of
medication review and reconciliation in Australian residential aged care facilities (RACF s) …
medication review and reconciliation in Australian residential aged care facilities (RACF s) …
Reducing the anticholinergic and sedative load in older patients on polypharmacy by pharmacist-led medication review: a randomised controlled trial
Objective To evaluate if a pharmacist-led medication review is effective at reducing the
anticholinergic/sedative load, as measured by the Drug Burden Index (DBI). Design …
anticholinergic/sedative load, as measured by the Drug Burden Index (DBI). Design …
Effect of a patient-centred deprescribing procedure in older multimorbid patients in Swiss primary care-A cluster-randomised clinical trial
S Zechmann, O Senn, F Valeri, S Essig, C Merlo… - BMC geriatrics, 2020 - Springer
Background Management of patients with polypharmacy is challenging, and evidence for
beneficial effects of deprescribing interventions is mixed. This study aimed to investigate …
beneficial effects of deprescribing interventions is mixed. This study aimed to investigate …
Polypharmacy and deprescribing: challenging the old and embracing the new
LK O'Donnell, K Ibrahim - BMC geriatrics, 2022 - Springer
People are living longer, and the World Health Organisation predicts that by 2050, 22% of
the world's population will be aged 60 years or older [1]. A common consequence of ageing …
the world's population will be aged 60 years or older [1]. A common consequence of ageing …