Advanced Diffusion‐Weighted MRI for Cancer Microstructure Assessment in Body Imaging, and Its Relationship With Histology

E Fokkinga, JA Hernandez‐Tamames… - Journal of Magnetic …, 2024 - Wiley Online Library
Diffusion‐weighted magnetic resonance imaging (DW‐MRI) aims to disentangle multiple
biological signal sources in each imaging voxel, enabling the computation of innovative …

Radiology and multi-scale data integration for precision oncology

H Paverd, K Zormpas-Petridis, H Clayton… - NPJ Precision …, 2024 - nature.com
In this Perspective paper we explore the potential of integrating radiological imaging with
other data types, a critical yet underdeveloped area in comparison to the fusion of other multi …

Avoiding unnecessary biopsy after multiparametric prostate MRI with VERDICT analysis: The INNOVATE study

S Singh, H Rogers, B Kanber, J Clemente, H Pye… - Radiology, 2022 - pubs.rsna.org
Background In men suspected of having prostate cancer (PCa), up to 50% of men with
positive multiparametric MRI (mpMRI) findings (Prostate Imaging Reporting and Data …

Validation of prostate tissue composition by using hybrid multidimensional MRI: correlation with histologic findings

A Chatterjee, C Mercado, RM Bourne, A Yousuf… - Radiology, 2022 - pubs.rsna.org
Background Tissue estimates obtained by using microstructure imaging techniques, such as
hybrid multidimensional (HM) MRI, may improve prostate cancer diagnosis but require …

The glial framework reveals white matter fiber architecture in human and primate brains

R Schurr, AA Mezer - Science, 2021 - science.org
Uncovering the architecture of white matter axons is fundamental to the study of brain
networks. We developed a method for quantifying axonal orientations at a resolution of~ 15 …

A multimodal computational pipeline for 3D histology of the human brain

M Mancini, A Casamitjana, L Peter, E Robinson… - Scientific reports, 2020 - nature.com
Ex vivo imaging enables analysis of the human brain at a level of detail that is not possible
in vivo with MRI. In particular, histology can be used to study brain tissue at the microscopic …

New prostate MRI techniques and sequences

A Chatterjee, C Harmath, A Oto - Abdominal Radiology, 2020 - Springer
Prostate MRI has seen increasing interest in recent years and has led to the development of
new MRI techniques and sequences to improve prostate cancer (PCa) diagnosis which are …

Joint estimation of relaxation and diffusion tissue parameters for prostate cancer with relaxation-VERDICT MRI

M Palombo, V Valindria, S Singh, E Chiou, F Giganti… - Scientific Reports, 2023 - nature.com
This work presents a biophysical model of diffusion and relaxation MRI for prostate called
relaxation vascular, extracellular and restricted diffusion for cytometry in tumours …

Emerging MR methods for improved diagnosis of prostate cancer by multiparametric MRI

DK Dwivedi, NR Jagannathan - Magnetic Resonance Materials in Physics …, 2022 - Springer
Current challenges of using serum prostate-specific antigen (PSA) level-based screening,
such as the increased false positive rate, inability to detect clinically significant prostate …

Metabolic imaging across scales reveals distinct prostate cancer phenotypes

N Sushentsev, G Hamm, L Flint, D Birtles… - Nature …, 2024 - nature.com
Hyperpolarised magnetic resonance imaging (HP-13C-MRI) has shown promise as a
clinical tool for detecting and characterising prostate cancer. Here we use a range of …