Tissue-resident macrophages (TRMs) are heterogeneous populations originating either
from monocytes or embryonic progenitors, and distribute in lymphoid and non-lymphoid …

The dance between microbes and the immune system takes place in all biological systems,
including the human body, but this interaction is especially complex in the primary gateway …

Inflammation is a defense mechanism that can protect the host against microbe invasion. A
proper inflammatory response can maintain homeostasis, but continuous inflammation can …

Immunoglobulin (Ig) superfamily proteins play diverse roles in vertebrates, including
regulation of cellular responses by sensing endogenous or exogenous ligands. Siglecs are …

Ancient genomes provide a tool to investigate the genetic basis of adaptations in extinct
organisms. However, the identification of species-specific fixed genetic variants requires the …

Simple Summary Hyperglycosylated cancer cells are often decorated with abundant sialic
acids, which are recognized by Sialic acid binding immunoglobulin type lectins (Siglecs) …

Coronaviruses (CoVs) are a diverse family of the enveloped human and animal viruses
reported as causative agents for respiratory and intestinal infections. The high pathogenic …

Macrophages are a type of functionally plastic cells that can create a pro-/anti-inflammatory
microenvironment for organs by producing different kinds of cytokines, chemokines, and …

Innate immune cells are able to build memory characteristics via a process termed “trained
immunity.” Host factors that influence the magnitude of the individual trained immunity …

The inflammasomes are intracellular multimeric protein complexes consisting of an innate
immune sensor, the adapter protein ASC and the inflammatory caspases-1 and/or-11 and …