Objective. Corneal neovascularization is a sight-threatening condition affecting more than
1.4 million people per year. Left untreated, it can lead to tissue scarring, oedema, lipid …

This review provides comprehensive information about the advances in gene therapy in the
anterior segment of the eye, including cornea, conjunctiva, lacrimal gland, and trabecular …

Genetic medicine is offering hope as new therapies are emerging for many previously
untreatable diseases. The eye is at the forefront of these advances, as exemplified by the …

Purpose: That vascular endothelial growth factor (VEGF) plays a major role in inflammatory
angiogenesis has been well established. This pilot study was designed to evaluate …

Corneal neovascularization (CNV) may be a physiological response to various stimuli, but a
chronic and persistent upregulation of neoangiogenesis can result in pathological CNV …

Cornea, a dome-shaped and transparent front part of the eye, affords 2/3rd refraction and
barrier functions. Globally, corneal diseases are the leading cause of vision impairment …

A large subset of corneal pathologies involves the formation of new blood and lymph
vessels (neovascularization), leading to compromised visual acuity. This article aims to …

Damage to the cornea from chemical burns is a serious clinical problem that often leads to
permanent visual impairment. Because transforming growth factor (TGF)-β has been …

Ocular angiogenesis, the formation of new vessels from the existing vascular tree, is a major
cause of severe vision loss. It can affect different structures in the eye, including the retina …

With no safe and efficient approved therapy available for treating corneal
neovascularization, the search for alternative and effective treatments is of great importance …