[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness
AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
[HTML][HTML] Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses
DM Morens, JK Taubenberger, AS Fauci - Cell host & microbe, 2023 - cell.com
Viruses that replicate in the human respiratory mucosa without infecting systemically,
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …
Mapping SARS-CoV-2 antigenic relationships and serological responses
During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic,
multiple variants escaping preexisting immunity emerged, causing reinfections of previously …
multiple variants escaping preexisting immunity emerged, causing reinfections of previously …
BA. 2 and BA. 5 omicron differ immunologically from both BA. 1 omicron and pre-omicron variants
Several studies have shown that SARS-CoV-2 BA. 1 omicron is an immune escape variant.
Meanwhile, however, omicron BA. 2 and BA. 5 became dominant in many countries and …
Meanwhile, however, omicron BA. 2 and BA. 5 became dominant in many countries and …
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history
W Wang, S Lusvarghi, R Subramanian, NJ Epsi… - Cell host & …, 2022 - cell.com
The rapid emergence of SARS-CoV-2 variants challenges vaccination strategies. Here, we
collected 201 serum samples from persons with a single infection or multiple vaccine …
collected 201 serum samples from persons with a single infection or multiple vaccine …
Antigenic mapping of emerging SARS-CoV-2 omicron variants BM. 1.1. 1, BQ. 1.1, and XBB. 1
AZ Mykytyn, ME Rosu, A Kok, M Rissmann… - The Lancet …, 2023 - thelancet.com
Novel SARS-CoV-2 omicron variants, including BM. 1.1. 1, BQ. 1.1, and XBB. 1, continue to
emerge at an unprecedented rate, evading preexisting immunity from vaccination and …
emerge at an unprecedented rate, evading preexisting immunity from vaccination and …
[HTML][HTML] Antigenic evolution of SARS coronavirus 2
AZ Mykytyn, RAM Fouchier, BL Haagmans - Current Opinion in Virology, 2023 - Elsevier
SARS coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, emerged in China in
December 2019. Vaccines developed were very effective initially, however, the virus has …
December 2019. Vaccines developed were very effective initially, however, the virus has …
Rapid escape of new SARS-CoV-2 Omicron variants from BA. 2-directed antibody responses
Summary In November 2021, Omicron BA. 1, containing a raft of new spike mutations,
emerged and quickly spread globally. Intense selection pressure to escape the antibody …
emerged and quickly spread globally. Intense selection pressure to escape the antibody …
SARS-CoV-2 Omicron BA. 1 breakthrough infection drives late remodeling of the memory B cell repertoire in vaccinated individuals
How infection by a viral variant showing antigenic drift impacts a preformed mature human
memory B cell (MBC) repertoire remains an open question. Here, we studied the MBC …
memory B cell (MBC) repertoire remains an open question. Here, we studied the MBC …
Safety and efficacy of the intranasal spray SARS-CoV-2 vaccine dNS1-RBD: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
F Zhu, S Huang, X Liu, Q Chen, C Zhuang… - The Lancet …, 2023 - thelancet.com
Background The live-attenuated influenza virus vector-based intranasal SARS-CoV-2
vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing …
vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing …