Noncovalent interactions, which usually feature tunable strength, reversibility, and
environmental adaptability, have been recognized as driving forces in a variety of biological …

Recent advances in nanostructured materials and unconventional device designs have
transformed the bioelectronics from a rigid and bulky form into a soft and ultrathin form and …

Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …

Inflammation-triggered combination delivery of anti-PD-1 antibody (aPD1) and CpG
oligodeoxynucleotides (CpG ODNs) has been demonstrated to prevent cancer relapse …

Conspectus Systemic administration of therapeutic agents has been the preferred approach
to treat most pathological conditions, in particular for cancer therapy. This treatment modality …

Local delivery of therapeutics for the treatment of inflammatory arthritis (IA) is limited by short
intra-articular half-lives. Since IA severity often fluctuates over time, a local drug delivery …