The road to malignant cell transformation after particulate matter exposure: from oxidative stress to genotoxicity

M Santibáñez-Andrade… - International journal of …, 2023 - mdpi.com
In cells, oxidative stress is an imbalance between the production/accumulation of oxidants
and the ability of the antioxidant system to detoxify these reactive products. Reactive oxygen …

Role of miRNA-19a in cancer diagnosis and poor prognosis

A Ardizzone, G Calabrese, M Campolo… - International journal of …, 2021 - mdpi.com
Cancer is a multifactorial disease that affects millions of people every year and is one of the
most common causes of death in the world. The high mortality rate is very often linked to late …

Isolation of phthalates and terephthalates from plant material–natural products or contaminants?

T Thiemann - Open Chemistry Journal, 2021 - benthamopen.com
Dialkyl phthalates have been used as plasticizers in polymers for decades. As mobile, small
weight molecules, phthalates have entered the environment, where they have become …

Deciphering the code between air pollution and disease: The effect of particulate matter on cancer hallmarks

M Santibáñez-Andrade, YI Chirino… - International journal of …, 2019 - mdpi.com
Air pollution has been recognized as a global health problem, causing around 7 million
deaths worldwide and representing one of the highest environmental crises that we are now …

Suppressive effects of rosmarinic acid rich fraction from perilla on oxidative stress, inflammation and metastasis ability in A549 cells exposed to PM via C-Jun, P-65-Nf …

K Pintha, W Chaiwangyen, S Yodkeeree, M Suttajit… - Biomolecules, 2021 - mdpi.com
Particulate matter from forest fires (PMFF) is an environmental pollutant causing oxidative
stress, inflammation, and cancer cell metastasis due to the presence of polycyclic aromatic …

Particulate Matter (PM10) Promotes Cell Invasion through Epithelial–Mesenchymal Transition (EMT) by TGF-β Activation in A549 Lung Cells

CM García-Cuellar, M Santibáñez-Andrade… - International Journal of …, 2021 - mdpi.com
Air pollution presents a major environmental problem, inducing harmful effects on human
health. Particulate matter of 10 μm or less in diameter (PM10) is considered an important risk …

1′-O-methyl-averantin isolated from the endolichenic fungus Jackrogersella sp. EL001672 suppresses colorectal cancer stemness via sonic Hedgehog and Notch …

M Varlı, EY Lee, Y Yang, R Zhou, İ Taş, S Pulat… - Scientific Reports, 2023 - nature.com
Endolichenic fungi are host organisms that live on lichens and produce a wide variety of
secondary metabolites. Colorectal cancer stem cells are capable of self-renewal and …

Inhalation of essential oil from Mentha piperita ameliorates PM10-exposed asthma by targeting IL-6/JAK2/STAT3 pathway based on a network pharmacological …

MH Kim, SJ Park, WM Yang - Pharmaceuticals, 2020 - mdpi.com
Fine particulate matter (PM) exposure exhibits a crucial risk factor to exacerbate airway
epithelial remodeling, fibrosis, and pulmonary destruction in asthma. Based on the use of …

An acetonic extract and secondary metabolites from the endolichenic fungus Nemania sp. EL006872 exhibit immune checkpoint inhibitory activity in lung cancer cell

M Varlı, HT Pham, SM Kim, İ Taş… - Frontiers in …, 2022 - frontiersin.org
Background: Endolichenic fungi (ELF), which live the inside the lichen thallus, contain many
secondary metabolites that show various biological activities. Recent studies show that …

A fatty acid-rich fraction of an endolichenic fungus Phoma sp. suppresses immune checkpoint markers via AhR/ARNT and ESR1

M Varlı, MT Ngo, SM Kim, İ Taş, R Zhou, CDB Gamage… - Heliyon, 2023 - cell.com
Lung cancer has the highest mortality rates worldwide. The disease is caused by
environmental pollutants, smoking, and many other factors. Recent treatments include …