[HTML][HTML] Study of tumor necrosis factor receptor in the inflammatory bowel disease

RF Souza, MAF Caetano, HIR Magalhães… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) and Crohn's disease (CD) are part of Inflammatory Bowel Diseases
(IBD) and have pathophysiological processes such as bowel necrosis and enteric neurons …

[HTML][HTML] Enteric nervous system and inflammatory bowel diseases: Correlated impacts and therapeutic approaches through the P2X7 receptor

HIR Magalhães, P Castelucci - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
The enteric nervous system (ENS) consists of thousands of small ganglia arranged in the
submucosal and myenteric plexuses, which can be negatively affected by Crohn's disease …

Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system

S Coquenlorge, E Duchalais, J Chevalier… - Journal of …, 2014 - Springer
Background Evidence continues to mount concerning the importance of the enteric nervous
system (ENS) in controlling numerous intestinal functions in addition to motility and epithelial …

Anatomical and functional changes to the colonic neuromuscular compartment after experimental spinal cord injury

AR White, GM Holmes - Journal of Neurotrauma, 2018 - liebertpub.com
A profound reduction in colorectal transit time accompanies spinal cord injury (SCI), yet the
colonic alterations after SCI have yet to be understood fully. The loss of descending …

Effects of a P2X7 receptor antagonist on myenteric neurons in the distal colon of an experimental rat model of ulcerative colitis

MM Evangelinellis, RF Souza, CE Mendes… - Histochemistry and Cell …, 2022 - Springer
Inflammatory bowel diseases (IBDs) are chronic diseases of the gastrointestinal tract that
include ulcerative colitis and Crohn's disease and affect enteric neurons. Research has …

Involvement of the P2X7 purinergic receptor in colonic motor dysfunction associated with bowel inflammation in rats

L Antonioli, MC Giron, R Colucci, C Pellegrini, D Sacco… - PloS one, 2014 - journals.plos.org
Background and Purpose Recent evidence indicates an involvement of P2X7 purinergic
receptor (P2X7R) in the fine tuning of immune functions, as well as in driving enteric neuron …

The role of extracellular adenosine triphosphate in ischemic organ injury

H Zhao, S Kilgas, A Alam, S Eguchi, D Ma - Critical care medicine, 2016 - journals.lww.com
Objectives: Ischemic tissue injury contributes to significant morbidity and mortality and is
implicated in a range of pathologic conditions, including but not limited to myocardial …

[HTML][HTML] Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis

HIR Magalhães, FA Machado, RF Souza… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND The literature indicates that the enteric nervous system is affected in
inflammatory bowel diseases (IBDs) and that the P2X7 receptor triggers neuronal death …

Differential effects of experimental ulcerative colitis on P2X7 receptor expression in enteric neurons

MV Da Silva, AR Marosti, CE Mendes… - Histochemistry and cell …, 2015 - Springer
The digestive tracts of ulcerative colitis and Crohn's disease patients present with
pathophysiological processes and intestinal necrosis. This study examined the P2X7 …

Submucosal neurons and enteric glial cells expressing the P2X7 receptor in rat experimental colitis

MV da Silva, AR Marosti, CE Mendes, K Palombit… - Acta …, 2017 - Elsevier
The aim of this study was to evaluate the effect of ulcerative colitis on the submucosal
neurons and glial cells of the submucosal ganglia of rats. 2, 4, 6-Trinitrobenzene sulfonic …