MicroRNA: function, detection, and bioanalysis
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
Extracellular microRNA: a new source of biomarkers
MicroRNAs (miRNAs) are a recently discovered class of small, non-coding RNAs that
regulate protein levels post-transcriptionally. miRNAs play important regulatory roles in …
regulate protein levels post-transcriptionally. miRNAs play important regulatory roles in …
Highly Sensitive MicroRNA Detection by Coupling Nicking-Enhanced Rolling Circle Amplification with MoS2 Quantum Dots
In this work, a label-free and highly sensitive fluorescence assay was constructed for
microRNA detection. Nicking-enhanced rolling circle amplification (RCA) induced by G …
microRNA detection. Nicking-enhanced rolling circle amplification (RCA) induced by G …
[HTML][HTML] MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics
The volume of point of care (POC) testing continues to grow steadily due to the increased
availability of easy-to-use devices, thus making it possible to deliver less costly care closer …
availability of easy-to-use devices, thus making it possible to deliver less costly care closer …
Single cell real-time miRNAs sensing based on nanomotors
A nanomotor-based strategy for rapid single-step intracellular biosensing of a target miRNA,
expressed in intact cancer cells, at the single cell level is described. The new concept relies …
expressed in intact cancer cells, at the single cell level is described. The new concept relies …
Ultrasensitive detection of microRNAs by exponential isothermal amplification
H Jia, Z Li, C Liu, Y Cheng - Angewandte Chemie, 2010 - infona.pl
Klitzekleine miRNA‐Mengen (bis hinab zu 0.1 zmol) lassen sich exakt und in Echtzeit
quantitativ bestimmen. Die hierfür eingesetzte Methode beruht auf einer exponentiellen …
quantitativ bestimmen. Die hierfür eingesetzte Methode beruht auf einer exponentiellen …
Two-tailed RT-qPCR: a novel method for highly accurate miRNA quantification
MicroRNAs are a class of small non-coding RNAs that serve as important regulators of gene
expression at the posttranscriptional level. They are stable in body fluids and pose great …
expression at the posttranscriptional level. They are stable in body fluids and pose great …
Three-dimensional DNA nanostructures to improve the hyperbranched hybridization chain reaction
J Wang, DX Wang, JY Ma, YX Wang, DM Kong - Chemical Science, 2019 - pubs.rsc.org
Nonenzymatic nucleic acid amplification techniques (eg the hybridization chain reaction,
HCR) have shown promising potential for amplified detection of biomarkers. However, the …
HCR) have shown promising potential for amplified detection of biomarkers. However, the …
Lab in a tube: ultrasensitive detection of microRNAs at the single-cell level and in breast cancer patients using quadratic isothermal amplification
R Duan, X Zuo, S Wang, X Quan, D Chen… - Journal of the …, 2013 - ACS Publications
Through rational design of a functional molecular probe with high sequence specificity that
takes advantage of sensitive isothermal amplification with simple operation, we developed a …
takes advantage of sensitive isothermal amplification with simple operation, we developed a …
Label-free nanoplasmonic-based short noncoding RNA sensing at attomolar concentrations allows for quantitative and highly specific assay of microRNA-10b in …
GK Joshi, S Deitz-McElyea, T Liyanage, K Lawrence… - ACS …, 2015 - ACS Publications
MicroRNAs are short noncoding RNAs consisting of 18–25 nucleotides that target specific
mRNA moieties for translational repression or degradation, thereby modulating numerous …
mRNA moieties for translational repression or degradation, thereby modulating numerous …