Porphyrins are heterocyclic macrocycle organic compounds, composed of four modified
pyrrole subunits interconnected at their α carbon atoms via methine bridges. Because of …

A lmost from its first reported use in humans in 1928 (l), sodium nitroprusside (SNP) has
been characterized as either villain or hero, depending on the clinician's assessment of the …

The concern of a terrorist attack using cyanide, as well as the gradual awareness of cyanide
poisoning in fire victims, has resulted in a renewed interest in the diagnosis and treatment of …

Cyanide poisoning causes a high incidence of severe symptomatology and fatality. There
are numerous sources of potential cyanide exposure. Without the history of cyanide …

Lactic acidosis in the setting of severe illness has a history dating back into the 1800s when
Johann Joseph Scherer first measured lactic acid levels in postmortem blood from two …

Cyanide is both widely available and easily accessible throughout the world. Although the
compound is not frequently encountered, it has been used as a poison and contaminant in …

Cyanide is a potent and rapidly‐acting asphyxiant which prevents tissue utilization of
oxygen by inhibition of the cellular respiratory enzyme, cytochrome oxidase. Inhalation or …

This Feature Article highlights recent developments in the field of vitamin B12 derivatives for
medicinal applications. The following topics are emphasized:(1) the development of …

Poisoning by hydrogen sulfide has been recognized as an occupational hazard for at least
two centuries. The development of alternative sources of energy in North America may …

To test whether changes in folate and vitamin B 12 nutrition modify the severity of potentially
premalignant lesions identified by cytology in sputum samples of smokers, we conducted a …