Antimicrobial peptides (AMPs) or host defense peptides protect the host against various
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …

Recognition of the natural abundance and functional importance of intrinsically disordered
proteins (IDPs), and protein hybrids that contain both intrinsically disordered protein regions …

In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Objective We explore here a novel model for amyloidogenesis in Alzheimer's disease (AD).
This new perspective on AD amyloidosis seeks to provide a rational framework for …

Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …

The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Cathelicidins are host defense peptides with antimicrobial and immunomodulatory functions.
These effector molecules of the innate immune system of many vertebrates are diverse in …

In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …

Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …