The importance of pyrimidines lies in the fact that they are structural components of a broad
spectrum of key molecules that participate in diverse cellular functions, such as synthesis of …

The eukaryotic microbes called oomycetes include many important saprophytes and
pathogens, with the latter exhibiting necrotrophy, biotrophy, or obligate biotrophy …

Downy mildews are obligate biotrophic oomycete pathogens that cause devastating plant
diseases on economically important crops. Plasmopara viticola is the causal agent of …

The oomycete pathogen Phytophthora infestans causes potato and tomato late blight, a
disease that is a serious threat to agriculture. P. infestans is a hemibiotrophic pathogen, and …

Fungicides have played a key role in crop disease control worldwide. However, resistance
development in pathogen populations became a serious concern in as early as 1970s and …

Oomycetes are a group of microorganisms that include pathogens responsible for
devastating diseases in plants and animals worldwide. Despite their importance, the …

Background Phytophthora infestans is responsible for late blight, one of the most important
potato diseases. Phenazine-1-carboxylic acid (PCA)-producing Pseudomonas fluorescens …

The target site of the novel fungicide quinofumelin was investigated in the rice blast fungus
Pyricularia oryzae. Quinofumelin-induced mycelial growth inhibition was reversed by orotate …

The Allium cepa L.(onion) crop is affected by leaf blight disease caused by Stemphylium
vesicarium; the shifts that S. vesicarium infection causes in the primary metabolism of onion …

Dihydroorotase (DHOase) is the third enzyme in the six enzymatic reaction steps of the
endogenous pyrimidine nucleotide de novo biosynthesis pathway, which is a metabolic …