Kaposi's sarcoma and its associated herpesvirus
EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …
VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
M Lohela, M Bry, T Tammela, K Alitalo - Current opinion in cell biology, 2009 - Elsevier
Vascular endothelial growth factors and their endothelial tyrosine kinase receptors are
central regulators of vasculogenesis, angiogenesis and lymphangiogenesis. VEGF …
central regulators of vasculogenesis, angiogenesis and lymphangiogenesis. VEGF …
[HTML][HTML] Lymphangiogenic factors, mechanisms, and applications
W Zheng, A Aspelund, K Alitalo - The Journal of clinical …, 2014 - Am Soc Clin Investig
Lymphangiogenesis, the growth of lymphatic vessels, is essential in embryonic
development. In adults, it is involved in many pathological processes such as lymphedema …
development. In adults, it is involved in many pathological processes such as lymphedema …
[HTML][HTML] Small-molecule inhibitors of the receptor tyrosine kinases: promising tools for targeted cancer therapies
M Hojjat-Farsangi - International journal of molecular sciences, 2014 - mdpi.com
Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of
the improvements in the life quality of patients, their effectiveness is compromised by several …
the improvements in the life quality of patients, their effectiveness is compromised by several …
VEGF‐C is required for intestinal lymphatic vessel maintenance and lipid absorption
Vascular endothelial growth factor C (VEGF‐C) binding to its tyrosine kinase receptor
VEGFR‐3 drives lymphatic vessel growth during development and in pathological …
VEGFR‐3 drives lymphatic vessel growth during development and in pathological …
Cediranib, an oral inhibitor of vascular endothelial growth factor receptor kinases, is an active drug in recurrent epithelial ovarian, fallopian tube, and peritoneal cancer
UA Matulonis, S Berlin, P Ivy, K Tyburski… - Journal of clinical …, 2009 - ascopubs.org
Purpose Angiogenesis is important for epithelial ovarian cancer (EOC) growth, and blocking
angiogenesis can lead to EOC regression. Cediranib is an oral tyrosine kinase inhibitor …
angiogenesis can lead to EOC regression. Cediranib is an oral tyrosine kinase inhibitor …
Vascular endothelial growth factor receptors VEGFR-2 and VEGFR-3 are localized primarily to the vasculature in human primary solid cancers
NR Smith, D Baker, NH James, K Ratcliffe… - Clinical Cancer …, 2010 - AACR
Purpose: Vascular endothelial growth factor (VEGF) signaling is key to tumor angiogenesis
and is an important target in the development of anticancer drugs. However, VEGF receptor …
and is an important target in the development of anticancer drugs. However, VEGF receptor …
Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer
S Tugues, S Koch, L Gualandi, X Li… - Molecular aspects of …, 2011 - Elsevier
Vascular endothelial growth factors (VEGFs) are critical regulators of vascular and lymphatic
function during development, in health and in disease. There are five mammalian VEGF …
function during development, in health and in disease. There are five mammalian VEGF …
Scholars and scientists in the history of the lymphatic system
The discovery of the lymphatic system has a long and fascinating history. The interest in
anatomy and physiology of this system paralleled that of the blood cardiocirculatory system …
anatomy and physiology of this system paralleled that of the blood cardiocirculatory system …
Targets for improving tumor response to radiotherapy
K Mortezaee, W Parwaie, E Motevaseli… - International …, 2019 - Elsevier
Radiotherapy is one of the most common treatment modalities for controlling a wide range of
tumors. However, it has been shown that radiotherapy alone is unable to completely …
tumors. However, it has been shown that radiotherapy alone is unable to completely …