Genomic dissection of inbreeding depression: a gate to new opportunities

I Curik, M Ferenčaković, J Sölkner - Revista Brasileira de Zootecnia, 2017 - SciELO Brasil
Inbreeding depression, reduction in performance of quantitative traits, including
reproduction and survival, caused by inbreeding, is a well-known phenomenon observed in …

Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle

E Peripolli, NB Stafuzza, DP Munari, ALF Lima… - BMC genomics, 2018 - Springer
Background Runs of homozygosity (ROH) are continuous homozygous segments of the
DNA sequence. They have been applied to quantify individual autozygosity and used as a …

Genome-wide scan for runs of homozygosity identifies potential candidate genes associated with local adaptation in Valle del Belice sheep

S Mastrangelo, M Tolone, MT Sardina, G Sottile… - Genetics Selection …, 2017 - Springer
Background Because very large numbers of single nucleotide polymorphisms (SNPs) are
now available throughout the genome, they are particularly suitable for the detection of …

Conservation status and historical relatedness of Italian cattle breeds

S Mastrangelo, E Ciani, P Ajmone Marsan… - Genetics Selection …, 2018 - Springer
Background In the last 50 years, the diversity of cattle breeds has experienced a severe
contraction. However, in spite of the growing diffusion of cosmopolite specialized breeds …

Insights into genetic diversity, runs of homozygosity and heterozygosity-rich regions in Maremmana semi-feral cattle using pedigree and genomic data

F Biscarini, S Mastrangelo, G Catillo, G Senczuk… - Animals, 2020 - mdpi.com
Simple Summary In this study, we estimated genetic diversity in semi-feral Maremmana
cattle using both pedigree-and genomic-based approaches, and detected regions of …

A comprehensive analysis of runs of homozygosity of eleven cattle breeds representing different production types

T Szmatoła, A Gurgul, I Jasielczuk, T Ząbek… - Animals, 2019 - mdpi.com
Simple Summary Runs of homozygosity (ROH) regions are known to be common in the
genomes of cattle and have become a subject of interest of various research in recent years …

Characteristics of runs of homozygosity in selected cattle breeds maintained in Poland

T Szmatoła, A Gurgul, K Ropka-Molik, I Jasielczuk… - Livestock Science, 2016 - Elsevier
Runs of homozygosity (ROH) are defined as contiguous homozygous regions of the genome
where the two haplotypes inherited from the parents are identical. It has been shown that the …

Genome-wide identification of runs of homozygosity islands and associated genes in local dairy cattle breeds

S Mastrangelo, MT Sardina, M Tolone, R Di Gerlando… - Animal, 2018 - cambridge.org
Runs of homozygosity (ROH) are widely used as predictors of whole-genome inbreeding
levels in cattle. They identify regions that have an unfavorable effect on a phenotype when …

Genomic regions underlying positive selection in local, Alpine cattle breeds

H Signer‐Hasler, L Casanova, A Barenco… - Animal …, 2023 - Wiley Online Library
We used genome‐wide SNP data from 18 local cattle breeds from six countries of the Alpine
region to characterize population structure and identify genomic regions underlying positive …

Genomic characterization of Pinzgau cattle: genetic conservation and breeding perspectives

V Kukučková, N Moravčíková, M Ferenčaković… - Conservation …, 2017 - Springer
A genome-wide scan of Slovak Pinzgau cattle was prepared for the first time in order to
estimate their genetic diversity at a more detailed level compared to previously published …