Mass spectrometry (MS) based proteomics have achieved a near-complete proteome
coverage in humans and in several other organisms, producing a wealth of information …

Targeted mass spectrometry‐based approaches are nowadays widely used for quantitative
proteomics studies and more recently have been implemented on high resolution/accurate …

Most proteomic studies use liquid chromatography coupled to tandem mass spectrometry to
identify and quantify the peptides generated by the proteolysis of a biological sample …

Selected reaction monitoring on a triple quadrupole mass spectrometer is currently
experiencing a renaissance within the proteomics community for its, as yet, unparalleled …

There is an immediate need for improved methods to systematically and precisely quantify
large sets of peptides in complex biological samples. To date protein quantification in …

Selected reaction monitoring (SRM) is a targeted mass spectrometric method that is
increasingly used in proteomics for the detection and quantification of sets of preselected …

In its early years, mass spectrometry (MS)-based proteomics focused on the cataloging of
proteins found in different species or different tissues. By 2005, proteomics was being used …

BACKGROUND Novel mass spectrometric techniques such as atmospheric pressure
ionization and tandem mass spectrometry have substantially extended the spectrum of …

The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in
translational research. This is particularly the case for the validation of protein biomarkers; …

Mass spectrometry platforms have attracted a lot of interest in the last 2 decades as profiling
tools for native peptides and proteins with clinical potential. However, limitations associated …