Over the past decades, great interest has been given to biomimetic nanoparticles (BNPs)
since the rise of targeted drug delivery systems and biomimetic nanotechnology. Biological …

Natural killer (NK) cells are a population of innate lymphoid cells playing a pivotal role in
host immune responses against infection and tumor growth. These cells have a powerful …

Therapeutic efficacy of a systemic drug delivery largely depends on the targeting design of
the delivery system, which tackles with circulatory traffic and prevents the nonspecific …

Despite advances in the diagnostic and therapeutic modalities, the prognosis of several
solid tumor malignancies remains poor. Different factors associated with solid tumors …

Equipping cancer-fighting immune cells with chimeric antigen receptor (CAR) has gained
immense attention for cancer treatment. CAR-engineered T cells (CAR T cells) are the first …

In treatments of solid tumors, adoptive transfer of ex vivo expanded natural killer (NK) cells
has dawned as a new paradigm. Compared with cytotoxic T lymphocytes, NK cells take a …

Introduction and methods In this study we report that sequential treatment of supercharged
NK (sNK) cells with either chemotherapeutic drugs or check-point inhibitors eliminate both …

We have recently shown that natural killer (NK) cells select and differentiate cancer stem
cells (CSCs)/undifferentiated tumors via secreted and membrane bound IFN-gamma (IFN-γ) …

Natural killer (NK) cells are known to target cancer stem cells and undifferentiated tumors. In
this paper, we provide a novel strategy for expanding large numbers of super-charged NK …

Therapeutic role of NK cells in solid tumors was challenged previously even though their
role in hematological malignancies has clearly been established. Furthermore, functions …