Oral delivery of nerolidol alleviates cyclophosphamide-induced renal inflammation, apoptosis, and fibrosis via modulation of NF-κB/cleaved caspase-3/TGF-β …

A Iqubal, AK Najmi, S Md, HM Alkreathy, J Ali… - Drug Delivery, 2023 - Taylor & Francis
Cyclophosphamide (CP) is one of the most extensively used antineoplastic drug, but the
nephrotoxicity caused by this drug is a major limiting factor for its use. Nerolidol (NERO) is a …

Biflavonoid quercetin protects against cyclophosphamide–induced organ toxicities via modulation of inflammatory cytokines, brain neurotransmitters, and astrocyte …

AY Onaolapo, FO Ojo, OJ Onaolapo - Food and chemical toxicology, 2023 - Elsevier
Background Cyclophosphamide use has been associated with increased oxidative stress in
cells and tissues. Quercetin's antioxidative properties make it of potential benefit in such …

[HTML][HTML] Protective effects of herbacetin against polystyrene microplastics-instigated liver damage in rats

Z Rafi, MU Ijaz, A Hamza, HA Khan, Z Ahmed… - Journal of King Saud …, 2024 - Elsevier
Polystyrene microplastics (PS-MPs) are raising global concerns as they have tendency to
induce adverse effects on organisms. Herbacetin (HBN) is a natural flavone that shows …

[HTML][HTML] Omarigliptin/rosinidin combination ameliorates cyclophosphamide-induced lung toxicity in rats: The interaction between glucagon-like peptide-1, TXNIP …

MA Abd Elmaaboud, AM Kabel, HM Borg… - Biomedicine & …, 2024 - Elsevier
Cyclophosphamide is an anti-neoplastic drug that has shown competence in the
management of a broad range of malignant tumors. In addition, it represents a keystone …

Protective potential of pterostilbene against cyclophosphamide-induced nephrotoxicity and cystitis in rats

G Kerimoğlu, T Arıcı, AF Bıyık, A Kulaber… - … Urology and Nephrology, 2023 - Springer
Purpose Cyclophosphamide (CYP) is an antitumor drug. However, in addition to its
antitumor affect, CYP can also lead to nephrotoxicity and hemorrhagic cystitis. The purpose …

Neuroprotective and cognitive enhancing effects of herbecetin against thioacetamide induced hepatic encephalopathy in rats via upregulation of AMPK and SIRT1 …

AA Sedik, DT Hussein, K Fathy, NA Mowaad - Scientific Reports, 2024 - nature.com
Acute liver injury, there is a risky neurological condition known as hepatic encephalopathy
(HE). Herbacetin is a glycosylated flavonoid with many pharmacological characteristics. The …

Nephroprotective Effect of Bergapten Against Cyclophosphamide-Mediated Renal Stress, Inflammation, and Fibrosis in Wistar Rats: Probable Role of NF-kB and TGF …

N Mohsin, MS Akhtar, SA Alkahtani, IA Walbi… - ACS …, 2024 - ACS Publications
Cyclophosphamide (CPM) is a well-established antineoplastic drug with marked clinical
outcomes in various types of cancers. Despite being a promising drug, its use is associated …

Boswellic Acid and Betulinic Acid Pre-treatments Can Prevent the Nephrotoxicity Caused by Cyclophosphamide Induction

M Berköz, O Çiftçi - Doklady Biochemistry and Biophysics, 2024 - Springer
Cyclophosphamide (CYP) is a chemotherapeutic drug used to treat various cancers.
However, its clinical use is limited due to severe organ damage, particularly to the kidneys …

草质素对巨噬细胞铁死亡效应的影响

孙伟翔, 张旺, 李昊达, 张婷, 秦枫, 袁亚梅, 张力… - 中国畜牧兽医, 2024 - chvm.net
[目的] 研究草质素对RAS-选择性致死小分子3 (RSL-3) 诱导的RAW264. 7
巨噬细胞铁死亡效应的抑制作用, 探究草质素对巨噬细胞铁死亡的影响.[方法] 利用0, 5, 10, 20 …

Assessment of mitochondrial function in neurotoxicology using alternative model organisms

DF Gonçalves, P Michelotti, AF da Silva… - Advances in …, 2023 - Elsevier
Mitochondria are organelles that supply the metabolic demands of cells, generating ATP by
two main driving forces: oxidative phosphorylation and electron transfer system. Beyond …