Conditioned Pain Modulation and Temporal Summation of Pain in Patients With Traumatic and Non-Specific Neck Pain: A Systematic Review and Meta-Analysis

A Arribas-Romano, J Fernández-Carnero… - The Journal of …, 2023 - Elsevier
In patients with neck pain, it is unclear whether pain inhibition and facilitation endogenous
pain mechanisms are altered. This systematic review and meta-analysis aimed to improve …

Gastrointestinal pain: A systematic review of temporal summation of pain paradigms and outcomes

D Huisman, M Mansfield, TM Cummins… - … Journal of Pain, 2024 - Wiley Online Library
Abstract Background and Objective Since targeted treatment for gastrointestinal pain is
elusive, identifying the mechanistic underpinning of this pain type is important. Facilitation of …

Drug discovery and development for fibromyalgia using practical biomarkers throughout the process from relevant animal models to patients

Y Nagakura, H Tozaki-Saitoh… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Fibromyalgia (FM) is a chronic pain condition characterized by widespread pain
and complex comorbidities with a high unmet medical need. Given few past successes in …

[HTML][HTML] Interplay between noxious heat sensitivity and temporal summation magnitude in patients with fibromyalgia and long-term opioid use

JD Bao, MA Rosser, SH Park, AK Baker… - Frontiers in …, 2023 - frontiersin.org
Introduction In chronic pain conditions such as fibromyalgia (FM), pain amplification within
the central nervous system, or “central sensitization,” may contribute to the development and …

Motor Cortex Inhibition and Facilitation Correlates with Fibromyalgia Compensatory Mechanisms and Pain: A Cross-Sectional Study

K Pacheco-Barrios, DC Pimenta, AV Pessotto, F Fregni - Biomedicines, 2023 - mdpi.com
The role of transcranial magnetic stimulation (TMS) measures as biomarkers of fibromyalgia
syndrome (FMS) phenotypes is still unclear. We aimed to determine the clinical correlates of …

Characterisation of the neurobiological phenotype of pain in psoriatic arthritis

F Sunzini - 2024 - theses.gla.ac.uk
Psoriatic arthritis (PsA) is a prevalent immune-mediated inflammatory arthritis marked by
chronic inflammation in both articular and periarticular regions. Advances in understanding …

The Peripheral Mechanisms of Musculoskeletal Pain

S Bharde - 2024 - qmro.qmul.ac.uk
A phenomenon commonly observed across various musculoskeletal (MSK) diseases, such
as osteoarthritis (OA), fibromyalgia syndrome (FMS), and persistent post-surgical pain …

Pain Sensitisation in Fibromyalgia. Cross-Sectional Associations between Quantitative Sensory Testing of Pain Sensitisation and Fibromyalgia Severity

SA Provan, PS Pettersen, T Haugmark, IJ Berg… - … Sensory Testing of … - papers.ssrn.com
BackgroundWhether fibromyalgia severity is related to measures of pain sensitisation,
assessed by quantitative sensory testing (QST), is not clear. ObjectiveTo examine the …