Inflammasomes are multiprotein complexes that activate inflammatory responses by
inducing pyroptosis and secretion of pro-inflammatory cytokines. Along with many previous …

Background The pattern recognition receptor Dectin-1 was initially discovered to play a
pivotal role in mediating pulmonary antifungal immunity and promoting neutrophil-driven …

Age-related hearing loss (ARHL) is a common issue associated with aging. One of the
typical causes of hearing loss is the damage to inner ear hair cells. In addition, oxidative …

Background Individuals with certain chronic inflammatory lung diseases have a higher risk
of developing lung cancer (LC). However, the underlying mechanisms remain largely …

The projects described within address a knowledge gap regarding specific epigenetic
regulatory mechanisms underlying the dysfunction of microglia in Alzheimer's disease. AD is …