Standard platelet concentrates (PCs) stored at 22° C have a limited shelf life of 5 days.
Because of the storage temperature, bacterial contamination of PCs can result in life …

Patients with chronic renal failure frequently show complex hemostatic disorders, the most
frequent being bleeding episodes. Hemorrhagic complications were more frequent and …

We have investigated the density of the collagen receptors glycoprotein VI (GPVI) and α2β1
on human platelets and their relationship to polymorphisms within the GPVI gene. GPVI …

Selectin-mediated tethering and rolling initiates the multi-step process of leukocyte
extravasation which is crucial for the formation of an inflammatory infiltrate. We studied the …

Factor XI binds to high affinity sites on the surface of stimulated platelets where it is efficiently
activated by thrombin. Here, we provide evidence that the factor XI binding site on platelets …

Platelets prepared in plasma can be frozen in 6% dimethyl sulfoxide (Me2SO) and stored for
extended periods at− 80° C. The aim of this study was to reduce the plasma present in the …

Review Page 1 Review CARDIAC BYPASS HAEMOSTASIS: PUTTING BLOOD THROUGH
THE MILL The burden of heart disease continues to increase (Sans et al, 1997), and coronary …

BACKGROUND Transfusion of cryopreserved platelets (cryoplatelets) is not common but
may replace standard liquid‐preserved platelets (PLTs) in specific circumstances. To better …

Activation of factor XI (FXI) by thrombin on stimulated platelets plays a physiological role in
hemostasis, providing additional thrombin generation required in cases of severe …

Objectives To investigate the differences between pre-and post-cardiopulmonary bypass
platelet function tests and to examine whether post-bypass tests could predict postoperative …