Resistance of lung cancer to EGFR-specific kinase inhibitors: activation of bypass pathways and endogenous mutators
I Marrocco, Y Yarden - Cancers, 2023 - mdpi.com
Simple Summary Genome-based cancer medicine is becoming the standard of care: the
patient's tumor DNA is first analyzed to identify driver mutations, and this permits later …
patient's tumor DNA is first analyzed to identify driver mutations, and this permits later …
[HTML][HTML] High throughput virtual screening and validation of Plant-Based EGFR L858R kinase inhibitors against Non-Small cell lung Cancer: An integrated approach …
K Gao, Z Chen, N Zhang, P Jiang - Saudi Pharmaceutical Journal, 2024 - Elsevier
Lung cancer ranks as the 2nd most common cancer globally. It's the most prevalent cancer
in men and the 2nd most common in women. The prominent events in EGFR-mutated non …
in men and the 2nd most common in women. The prominent events in EGFR-mutated non …
Impact of synthesis methods on the functionality of antibody-conjugated gold nanoparticles for targeted therapy
A Anaki, C Tzror-Azankot, M Motiei, T Sadan… - Nanoscale …, 2024 - pubs.rsc.org
Gold nanoparticles (GNPs) are emerging as promising modular platforms for antibody-
based cancer therapeutics. Their unique physiochemical properties enable efficient binding …
based cancer therapeutics. Their unique physiochemical properties enable efficient binding …
Prognostic Factors and Markers in Non-Small Cell Lung Cancer: Recent Progress and Future Challenges
DD Meira, MC de Castro e Caetano, MC Casotti… - Genes, 2023 - mdpi.com
Lung cancer is a highly aggressive neoplasm and, despite the development of recent
therapies, tumor progression and recurrence following the initial response remains …
therapies, tumor progression and recurrence following the initial response remains …
Computational insights into the stereo-selectivity of catechins for the inhibition of the cancer therapeutic target EGFR kinase
The epidermal growth factor receptor (EGFR) plays a crucial role in regulating cellular
growth and survival, and its dysregulation is implicated in various cancers, making it a prime …
growth and survival, and its dysregulation is implicated in various cancers, making it a prime …
A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
A Simoni-Nieves, M Lindzen, S Giri, N Gupta… - Cell Reports …, 2024 - cell.com
Activating EGFR (epidermal growth factor receptor) mutations can be inhibited by specific
tyrosine kinase inhibitors (TKIs), which have changed the landscape of lung cancer therapy …
tyrosine kinase inhibitors (TKIs), which have changed the landscape of lung cancer therapy …
[PDF][PDF] de Castro e Caetano
DD Meira - lung cancer, 2023 - academia.edu
Lung cancer is a highly aggressive neoplasm and, despite the development of recent
therapies, tumor progression and recurrence following the initial response remains …
therapies, tumor progression and recurrence following the initial response remains …
Precision genome editing screens to study genetic variants of uncertain significance
O Belli - 2024 - research-collection.ethz.ch
Genetic tests play an increasingly pivotal role in predicting disease risks, prognosis and
treatment response in the clinics. However, their interpretation is hindered by the prevalence …
treatment response in the clinics. However, their interpretation is hindered by the prevalence …