For clinicians grappling with quantifying the complex spatial and temporal patterns of
cardiac structure and function (such as myocardial trabeculae, coronary microvascular …

Myosin heavy chain gene 7 (MYH7), a sarcomeric gene encoding the myosin heavy chain
(myosin-7), has attracted considerable interest as a result of its fundamental functions in …

Introduction Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited heart
disease. Next-generation sequencing (NGS) is the preferred genetic test, but the diagnostic …

Increasing evidence suggests that both coding and non-coding regions of sarcomeric
protein genes can contribute to hypertrophic cardiomyopathy (HCM). Here, we introduce an …

Background: Mutations in at least 30 genes have been linked to hypertrophic
cardiomyopathy (HCM). Due to the large size of the main HCM genes, Sanger sequencing is …

Aim: The long noncoding RNA H19 and its host micro RNA miR-675 have been found
deregulated in cardiac hypertrophy and heart failure tissues. Our aim was to investigate …

ABSTRACT INTRODUCTION Hypertrophic cardiomyopathy (HCM) is a heart disorder
caused by autosomal dominant alterations affecting both sarcomeric genes and other …

Over the last ten years, analysis of copy number variants has increasingly been applied to
the study of arrhythmogenic pathologies associated with sudden death, mainly due to …

Обзор посвящен анализу вариабельности клинических проявлений неоднократно
зарегистрированного у пациентов с гипертрофической кардиомиопатией (ГКМП) …

Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide,
despite the wide diversity of molecular targets identified and the development of therapeutic …