Non‐covalent interactions play a crucial role in (supramolecular) chemistry and much of
biology. Supramolecular forces can indeed determine the structure and function of a host …

σ‐Holes and π‐holes are two types of regions of lower electronic density that are frequently
found in molecules. There are often positive electrostatic potentials associated with them …

A covalently-bonded atom typically has a region of lower electronic density, a “σ-hole,” on
the side of the atom opposite to the bond, along its extension. There is frequently a positive …

The element selenium was discovered in 1818 by the Swedish chemist Berzelius and was
named after the Greek goddess of the moon, Selene. 1 In biology, selenium was long …

The nature of halogen-halogen interactions in crystals has long been a matter of interest and
debate. 2 Intermolecular interactions associated with distances shorter than the sum of the …

In 1836 the first organoselenium compound, diethyl selenide, was prepared by Löwig, 1 and
it was isolated in the pure form in 1869. 2 Early selenium chemistry involved the synthesis of …

Tetrel (Tr) bonding is first placed into perspective as a σ‐hole bonding interaction with atoms
of the Tr family. An sp3 R4Tr unit has four σ‐holes with which a Lewis base can form a …

To understand the intermolecular interactions between chalcogen centers (O, S, Se, Te),
quantum chemical calculations on pairs of model systems were carried out. For the oxygen …

It follows from the Schrödinger equation that the forces operating within molecules and
molecular complexes are Coulombic, which necessarily entails both electrostatics and …

After a brief discussion of the σ-hole concept and the significance of molecular electrostatic
potentials in noncovalent interactions, we draw attention to some common misconceptions …