Brachytherapy future directions

JAM Cunha, R Flynn, C Bélanger, C Callaghan… - Seminars in radiation …, 2020 - Elsevier
Brachytherapy has advanced dramatically in the last decade due largely to improvements in
applicators, imaging, treatment planning, and use of clinical trials. In addition, current …

Optimization in treatment planning of high dose‐rate brachytherapy—Review and analysis of mathematical models

B Morén, T Larsson, ÅC Tedgren - Medical Physics, 2021 - Wiley Online Library
Treatment planning in high dose‐rate brachytherapy has traditionally been conducted with
manual forward planning, but inverse planning is today increasingly used in clinical practice …

Guidelines by the AAPM and GEC‐ESTRO on the use of innovative brachytherapy devices and applications: Report of Task Group 167

R Nath, MJ Rivard, LA DeWerd, WA Dezarn… - Medical …, 2016 - Wiley Online Library
Although a multicenter, Phase III, prospective, randomized trial is the gold standard for
evidence‐based medicine, it is rarely used in the evaluation of innovative devices because …

A novel 169Yb‐based dynamic‐shield intensity modulated brachytherapy delivery system for prostate cancer

G Famulari, M Duclos, SA Enger - Medical physics, 2020 - Wiley Online Library
Purpose Intensity modulated brachytherapy (IMBT) is a novel high dose rate brachytherapy
(HDR BT) technique which incorporates static or dynamic shielding to increase tumor …

Systematic review of intensity-modulated brachytherapy (IMBT): static and dynamic techniques

CM Callaghan, Q Adams, RT Flynn, X Wu, W Xu… - International Journal of …, 2019 - Elsevier
Purpose To systematically review scientific literature on the use of intensity-modulated
brachytherapy (IMBT), including static and dynamic shielding approaches, to enhance …

Microdosimetric evaluation of current and alternative brachytherapy sources—a Geant4-DNA simulation study

G Famulari, P Pater, SA Enger - International Journal of Radiation …, 2018 - Elsevier
Purpose Radioisotopes such as 75 Se, 169 Yb, and 153 Gd have photon energy spectra
and half-lives that make them excellent candidates as alternatives to 192 Ir for high-dose …

Direction modulated brachytherapy (DMBT) for treatment of cervical cancer: A planning study with 192Ir, 60Co, and 169Yb HDR sources

H Safigholi, DY Han, S Mashouf, A Soliman… - Medical …, 2017 - Wiley Online Library
Purpose To evaluate plan quality of a novel MRI‐compatible direction modulated
brachytherapy (DMBT) tandem applicator using 192Ir, 60Co, and 169Yb HDR …

A directional 103Pd brachytherapy device: Dosimetric characterization and practical aspects for clinical use

MJ Rivard - Brachytherapy, 2017 - Elsevier
Purpose A brachytherapy (BT) device has been developed with shielding to provide
directional BT for preferentially irradiating malignancies while sparing healthy tissues. The …

A novel minimally invasive dynamic‐shield, intensity‐modulated brachytherapy system for the treatment of cervical cancer

M Morcos, M Antaki, AN Viswanathan… - Medical …, 2021 - Wiley Online Library
Purpose To present a novel, MRI‐compatible dynamicshield intensity modulated
brachytherapy (IMBT) applicator and delivery system using 192Ir, 75Se, and 169Yb …

Efficient 169Yb high‐dose‐rate brachytherapy source production using reactivation

RT Flynn, QE Adams, KM Hopfensperger, X Wu… - Medical …, 2019 - Wiley Online Library
Purpose To present and quantify the effectiveness of a method for the efficient production of
169Yb high‐dose‐rate brachytherapy sources with 27 Ci activity upon clinical delivery …