RNA-Binding Proteins: A Role in Neurotoxicity?
A Ocharán-Mercado, J Loaeza-Loaeza… - Neurotoxicity …, 2023 - Springer
Despite sustained efforts to treat neurodegenerative diseases, little is known at the
molecular level to understand and generate novel therapeutic approaches for these …
molecular level to understand and generate novel therapeutic approaches for these …
Dead end and Detour: The function of the RNA-binding protein Dnd in posttranscriptional regulation in the germline
T Gross-Thebing, E Raz - Current topics in developmental biology, 2020 - Elsevier
Posttranscriptional regulation is a key part of controlling gene expression in different cell
types, in particular in the context of specification, maintenance and differentiation of germline …
types, in particular in the context of specification, maintenance and differentiation of germline …
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell …
VA Ruthig, MB Friedersdorf, JA Garness… - …, 2019 - journals.biologists.com
The adult spermatogonial stem cell population arises from pluripotent primordial germ cells
(PGCs) that enter the fetal testis around embryonic day (E) 10.5. PGCs undergo rapid mitotic …
(PGCs) that enter the fetal testis around embryonic day (E) 10.5. PGCs undergo rapid mitotic …
A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells
VA Ruthig, T Yokonishi, MB Friedersdorf… - Biology of …, 2021 - academic.oup.com
In vertebrates, the RNA-binding protein (RBP) dead end 1 (DND1) is essential for primordial
germ cell (PGC) survival and maintenance of cell identity. In multiple species, Dnd1 loss or …
germ cell (PGC) survival and maintenance of cell identity. In multiple species, Dnd1 loss or …
Dead-End (dnd) Gene Cloning and Gonad-Specific Expression Pattern in Starry Flounder (Platichthys stellatus)
JH Yoon, YS Cho, HB Lee, JY Park, HK Lim - Animals, 2021 - mdpi.com
Simple Summary The dead end (dnd) gene encodes an RNA-binding protein that plays a
role for migration of primordial germ cells (PGCs) to the gonadal region during …
role for migration of primordial germ cells (PGCs) to the gonadal region during …
A cooperative mechanism of target RNA selection via germ-cell-specific RNA-binding proteins NANOS2 and DND1
The germ-cell-specific RNA-binding protein (RBP) NANOS2 plays a pivotal role in male
gonocyte differentiation and spermatogonial stem cell maintenance. Although NANOS2 …
gonocyte differentiation and spermatogonial stem cell maintenance. Although NANOS2 …
The structure of yeast Npl3 bound to RNA reveals a cooperative sequence-specific recognition and an RNA chaperone role in splicing
A Moursy, A Cléry, S Gerhardy, KM Betz, S Rao… - bioRxiv, 2022 - biorxiv.org
The conserved SR-like protein Npl3 promotes splicing of diverse pre-mRNAs. However, the
RNA sequence (s) recognized by the RNA Recognition Motifs (RRM1 & RRM2) of Npl3 …
RNA sequence (s) recognized by the RNA Recognition Motifs (RRM1 & RRM2) of Npl3 …
[PDF][PDF] Studies on the function and target-RNA recognition of RNA-binding proteins essential for mouse germ cell differentiation
D Wright - (No Title), 2021 - ir.soken.ac.jp
Post-transcriptional regulation by RNA-binding proteins (RBPs) is highly important to
establish gene regulatory networks during all stages of germ cell development. RBPs …
establish gene regulatory networks during all stages of germ cell development. RBPs …
Studies on the function and target-RNA recognition of RNA-binding proteins essential for mouse germ cell differentiation (マウスの生殖細胞の分化に必須なRNA 結合 …
ライトダネル - ir.soken.ac.jp
Post-transcriptional regulation by RNA-binding proteins (RBPs) is highly important to
establish gene regulatory networks during all stages of germ cell development. RBPs …
establish gene regulatory networks during all stages of germ cell development. RBPs …