Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …
may increase the risk for heart failure development. This risk evolves from functional and …
[HTML][HTML] Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3
Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …
[HTML][HTML] An updated insight into molecular mechanism of hydrogen sulfide in cardiomyopathy and myocardial ischemia/reperfusion injury under diabetes
Cardiovascular diseases are the most common complications of diabetes, and diabetic
cardiomyopathy is a major cause of people death in diabetes. Molecular, transcriptional …
cardiomyopathy is a major cause of people death in diabetes. Molecular, transcriptional …
[HTML][HTML] Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy
QB Lu, Y Ding, Y Liu, ZC Wang, YJ Wu, KM Niu… - Journal of advanced …, 2023 - Elsevier
Abstract Introduction Meteorin-like hormone (Metrnl) is ubiquitously expressed in skeletal
muscle, heart, and adipose with beneficial roles in obesity, insulin resistance, and …
muscle, heart, and adipose with beneficial roles in obesity, insulin resistance, and …
Poly (pentahydropyrimidine)‐Based Hybrid Hydrogel with Synergistic Antibacterial and Pro‐Angiogenic Ability for the Therapy of Diabetic Foot Ulcers
Bacterial infection and impaired angiogenesis make the treatment of diabetic foot ulcers
(DFU) extremely challenging. Cationic polymers are expected to treat infected wounds due …
(DFU) extremely challenging. Cationic polymers are expected to treat infected wounds due …
Fucoxanthin ameliorated myocardial fibrosis in STZ-induced diabetic rats and cell hypertrophy in HG-induced H9c2 cells by alleviating oxidative stress and restoring …
D Zheng, L Chen, G Li, L Jin, Q Wei, Z Liu, G Yang… - Food & Function, 2022 - pubs.rsc.org
Diabetic cardiomyopathy (DCM) is one of the leading causes of death in diabetic patients,
and is accompanied by increased oxidative stress and mitochondrial dysfunction …
and is accompanied by increased oxidative stress and mitochondrial dysfunction …
Chicoric acid ameliorates sepsis-induced cardiomyopathy via regulating macrophage metabolism reprogramming
HJ Sun, GL Zheng, ZC Wang, Y Liu, N Bao, PX Xiao… - Phytomedicine, 2024 - Elsevier
Background Sepsis-related cardiac dysfunction is believed to be a primary cause of high
morbidity and mortality. Metabolic reprogramming is closely linked to NLRP3 inflammasome …
morbidity and mortality. Metabolic reprogramming is closely linked to NLRP3 inflammasome …
Expanding the frontiers of guardian antioxidant selenoproteins in cardiovascular pathophysiology
Significance: Physiological levels of reactive oxygen and nitrogen species (ROS/RNS)
function as fundamental messengers for many cellular and developmental processes in the …
function as fundamental messengers for many cellular and developmental processes in the …
Roles of circular RNAs in diabetic complications: from molecular mechanisms to therapeutic potential
JR Zhang, HJ Sun - Gene, 2020 - Elsevier
Diabetes is characterized by changed homeostasis of blood glucose levels, which is
associated with various complications, including cardiomyopathy, atherosclerosis …
associated with various complications, including cardiomyopathy, atherosclerosis …
Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy
W Gong, Q Jiao, J Yuan, H Luo, Y Liu, Y Zhang… - Clinical …, 2023 - portlandpress.com
Previous studies of the Caveolin 1 (Cav1) protein and caveolae, which are lipid raft
structures found on the plasma membranes of certain cells, are associated with fat …
structures found on the plasma membranes of certain cells, are associated with fat …