Emerging CRISPR Therapies for Precision Gene Editing and Modulation in the Cardiovascular Clinic
NJ Legere, JT Hinson - Current Cardiology Reports, 2024 - Springer
Many iterations of the original CRISPR system have been developed seeking to leverage its
vast therapeutic potential. As examples, nuclease-free editing, precision single-nucleotide …
vast therapeutic potential. As examples, nuclease-free editing, precision single-nucleotide …
Generation of induced pluripotent stem cells from an individual with early onset and severe hypertrophic cardiomyopathy linked to MYBPC3: c.772G > A mutation
M Ribeiro, J Jager, M Furtado, T Carvalho, JMS Cabral… - Human Cell, 2024 - Springer
Hypertrophic cardiomyopathy (HCM) is frequently caused by mutations in the MYPBC3
gene, which encodes the cardiac myosin-binding protein C (cMyBP-C). Most pathogenic …
gene, which encodes the cardiac myosin-binding protein C (cMyBP-C). Most pathogenic …