A review of ApoE4 interference targeting Mitophagy molecular pathways for Alzheimer's disease
H Chen, F Chen, Y Jiang, L Zhang, G Hu… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is one of the major worldwide causes of dementia that is
characterized by irreversible decline in learning, memory loss, and behavioral impairments …
characterized by irreversible decline in learning, memory loss, and behavioral impairments …
Mitochondria in Alzheimer's disease pathogenesis
AB Reiss, S Gulkarov, B Jacob, A Srivastava… - Life, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disorder that
primarily affects persons aged 65 years and above. It causes dementia with memory loss …
primarily affects persons aged 65 years and above. It causes dementia with memory loss …
[HTML][HTML] Decreased miR-451a in cerebrospinal fluid, a marker for both cognitive impairment and depressive symptoms in Alzheimer's disease
H Feng, P Hu, Y Chen, H Sun, J Cai, X He, Q Cao… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Alzheimer's disease (AD) patients are often accompanied by depressive
symptoms, but its underlying mechanism remains unclear. The present study aimed to …
symptoms, but its underlying mechanism remains unclear. The present study aimed to …
Diastolic dysfunction in Alzheimer's disease model mice is associated with Aβ-amyloid aggregate formation and mitochondrial dysfunction
Alzheimer's Disease (AD) is a progressive neurodegenerative disease caused by the
deposition of Aβ aggregates or neurofibrillary tangles. AD patients are primarily diagnosed …
deposition of Aβ aggregates or neurofibrillary tangles. AD patients are primarily diagnosed …
Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta in mouse model of Alzheimer's …
FJ Mirza, S Zahid - Frontiers in Pharmacology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a multifaceted neurodegenerative disorder characterized by
substantial neuronal damage which manifests in the form of deficits in memory and …
substantial neuronal damage which manifests in the form of deficits in memory and …
[HTML][HTML] GV1001 modulates neuroinflammation and improves memory and behavior through the activation of gonadotropin-releasing hormone receptors in a triple …
H Park, HS Kwon, KY Lee, YE Kim, JW Son… - Brain, Behavior, and …, 2024 - Elsevier
GV1001 protects neural cells from amyloid-β (Aβ) toxicity and other stressors in in vitro
studies and demonstrates clinically beneficial effects in patients with moderate to severe …
studies and demonstrates clinically beneficial effects in patients with moderate to severe …
Loss of cholinergic receptor muscarinic 1 impairs cortical mitochondrial structure and function: implications in Alzheimer's disease
MG Sabbir, M Swanson, BC Albensi - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Cholinergic Receptor Muscarinic 1 (CHRM1) is a G protein-coupled
acetylcholine (ACh) receptor predominantly expressed in the cerebral cortex. In a …
acetylcholine (ACh) receptor predominantly expressed in the cerebral cortex. In a …
DNA Damage and Parkinson's Disease
GP Pfeifer - International Journal of Molecular Sciences, 2024 - mdpi.com
The etiology underlying most sporadic Parkinson's' disease (PD) cases is unknown.
Environmental exposures have been suggested as putative causes of the disease. In cell …
Environmental exposures have been suggested as putative causes of the disease. In cell …
Biomarker evidence of early vision and rod energy-linked pathophysiology benefits from very low dose DMSO in 5xFAD mice
BA Berkowitz, A Paruchuri, J Stanek… - Acta Neuropathologica …, 2024 - Springer
Here, we test whether early visual and OCT rod energy-linked biomarkers indicating
pathophysiology in nicotinamide nucleotide transhydrogenase (Nnt)-null 5xFAD mice also …
pathophysiology in nicotinamide nucleotide transhydrogenase (Nnt)-null 5xFAD mice also …
[HTML][HTML] Drp1 and neuroinflammation: Deciphering the interplay between mitochondrial dynamics imbalance and inflammation in neurodegenerative diseases
P Cai, W Li, Y Xu, H Wang - Neurobiology of Disease, 2024 - Elsevier
Neuroinflammation and mitochondrial dysfunction are closely intertwined with the
pathophysiology of neurological disorders. Recent studies have elucidated profound …
pathophysiology of neurological disorders. Recent studies have elucidated profound …